Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Characterization of X-chromosome inactivation status in human pluripotent stem cells.
Characterization of Xpr (Xpct) reveals instability but no effects on X-chromosome pairing or Xist expression.
Authors: Authors: Sun S, Fukue Y, Nolen L, Sadreyev R, Lee JT.
Transcription
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Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene.
Authors: Authors: Zhou D, Conrad C, Xia F, Park JS, Payer B, Yin Y, Lauwers GY, Thasler W, Lee JT, Avruch J, Bardeesy N.
Cancer Cell
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Cancer Cell
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Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome.
The pluripotency factor Oct4 interacts with Ctcf and also controls X-chromosome pairing and counting.
Authors: Authors: Donohoe ME, Silva SS, Pinter SF, Xu N, Lee JT.
Nature
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Nature
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Telomeric RNAs mark sex chromosomes in stem cells.
Authors: Authors: Zhang LF, Ogawa Y, Ahn JY, Namekawa SH, Silva SS, Lee JT.
Genetics
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Genetics
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XY and ZW: is meiotic sex chromosome inactivation the rule in evolution?
Characterization of two Mst1-deficient mouse models.
Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome.
Jeannie T. Lee.