Jeannie Lee headshot

Jeannie T. Lee, M.D., Ph.D.

Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
617-726-5943
Lee Lab Website
Toward a consensus on the binding specificity and promiscuity of PRC2 for RNA.
Authors: Authors: Davidovich C, Wang X, Cifuentes-Rojas C, Goodrich KJ, Gooding AR, Lee JT, Cech TR.
Mol Cell
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Locus-specific targeting to the X chromosome revealed by the RNA interactome of CTCF.
Authors: Authors: Kung JT, Kesner B, An JY, Ahn JY, Cifuentes-Rojas C, Colognori D, Jeon Y, Szanto A, del Rosario BC, Pinter SF, Erwin JA, Lee JT.
Mol Cell
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Building the Connectivity Map of epigenetics: chromatin profiling by quantitative targeted mass spectrometry.
Authors: Authors: Creech AL, Taylor JE, Maier VK, Wu X, Feeney CM, Udeshi ND, Peach SE, Boehm JS, Lee JT, Carr SA, Jaffe JD.
Methods
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ATRX directs binding of PRC2 to Xist RNA and Polycomb targets.
Authors: Authors: Sarma K, Cifuentes-Rojas C, Ergun A, Del Rosario A, Jeon Y, White F, Sadreyev R, Lee JT.
Cell
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Regulatory interactions between RNA and polycomb repressive complex 2.
Authors: Authors: Cifuentes-Rojas C, Hernandez AJ, Sarma K, Lee JT.
Mol Cell
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Long noncoding RNAs: fresh perspectives into the RNA world.
Authors: Authors: Yang L, Froberg JE, Lee JT.
Trends Biochem Sci
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Coupling of X-chromosome reactivation with the pluripotent stem cell state.
Authors: Authors: Payer B, Lee JT.
RNA Biol
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Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming.
Authors: Authors: Payer B, Rosenberg M, Yamaji M, Yabuta Y, Koyanagi-Aoi M, Hayashi K, Yamanaka S, Saitou M, Lee JT.
Mol Cell
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High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation.
Authors: Authors: Simon MD, Pinter SF, Fang R, Sarma K, Rutenberg-Schoenberg M, Bowman SK, Kesner BA, Maier VK, Kingston RE, Lee JT.
Nature
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Guided by RNAs: X-inactivation as a model for lncRNA function.
Authors: Authors: Froberg JE, Yang L, Lee JT.
J Mol Biol
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