Jeannie T. Lee, M.D., Ph.D.
Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital
Vice Chair of the Department of Genetics, Harvard Medical School
Professor of Genetics and Pathology, Harvard Medical School
Jpx RNA activates Xist by evicting CTCF.
Authors: Authors: Sun S, Del Rosario BC, Szanto A, Ogawa Y, Jeon Y, Lee JT.
Cell
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Cell
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Bimodal quantitative relationships between histone modifications for X-linked and autosomal loci.
Authors: Authors: Sadreyev RI, Yildirim E, Pinter SF, Lee JT.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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RNA in the loop.
X-inactivation, imprinting, and long noncoding RNAs in health and disease.
Long noncoding RNAs: past, present, and future.
Xist RNA is a potent suppressor of hematologic cancer in mice.
Authors: Authors: Yildirim E, Kirby JE, Brown DE, Mercier FE, Sadreyev RI, Scadden DT, Lee JT.
Cell
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Cell
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X chromosome inactivation and epigenetic responses to cellular reprogramming.
Authors: Authors: Lessing D, Anguera MC, Lee JT.
Annu Rev Genomics Hum Genet
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Annu Rev Genomics Hum Genet
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Epigenetic regulation by long noncoding RNAs.
ALKBH1 is a histone H2A dioxygenase involved in neural differentiation.
Authors: Authors: Ougland R, Lando D, Jonson I, Dahl JA, Moen MN, Nordstrand LM, Rognes T, Lee JT, Klungland A, Kouzarides T, Larsen E.
Stem Cells
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Stem Cells
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An ex vivo model for imprinting: mutually exclusive binding of Cdx2 and Oct4 as a switch for imprinted and random X-inactivation.