Jeannie T. Lee

Jeannie T. Lee, M.D., Ph.D.

Phillip A. Sharp Chair in Molecular Biology, Massachusetts General Hospital

Vice Chair of the Department of Genetics, Harvard Medical School

Professor of Genetics and Pathology, Harvard Medical School

617-726-5943

Lee Lab Website

Publications

Spreading of X chromosome inactivation via a hierarchy of defined Polycomb stations.

Authors: Authors: Pinter SF, Sadreyev RI, Yildirim E, Jeon Y, Ohsumi TK, Borowsky M, Lee JT.
Genome Res 2012-10-01
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Molecular signatures of human induced pluripotent stem cells highlight sex differences and cancer genes.

Authors: Authors: Anguera MC, Sadreyev R, Zhang Z, Szanto A, Payer B, Sheridan SD, Kwok S, Haggarty SJ, Sur M, Alvarez J, Gimelbrant A, Mitalipova M, Kirby JE, Lee JT.
Cell Stem Cell 2012-07-06
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New and Xisting regulatory mechanisms of X chromosome inactivation.

Authors: Authors: Jeon Y, Sarma K, Lee JT.
Curr Opin Genet Dev 2012-04-01
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X-chromosome hyperactivation in mammals via nonlinear relationships between chromatin states and transcription.

Authors: Authors: Yildirim E, Sadreyev RI, Pinter SF, Lee JT.
Nat Struct Mol Biol 2011-12-04
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Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control.

Authors: Authors: Lee JT.
Nat Rev Mol Cell Biol 2011-11-23
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A boundary element between Tsix and Xist binds the chromatin insulator Ctcf and contributes to initiation of X-chromosome inactivation.

Authors: Authors: Spencer RJ, del Rosario BC, Pinter SF, Lessing D, Sadreyev RI, Lee JT.
Genetics 2011-10-01
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Tsx produces a long noncoding RNA and has general functions in the germline, stem cells, and brain.

Authors: Authors: Anguera MC, Ma W, Clift D, Namekawa S, Kelleher RJ, Lee JT.
PLoS Genet 2011-09-01
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X-inactivation and X-reactivation: epigenetic hallmarks of mammalian reproduction and pluripotent stem cells.

Authors: Authors: Payer B, Lee JT, Namekawa SH.
Hum Genet 2011-08-01
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YY1 tethers Xist RNA to the inactive X nucleation center.

Authors: Authors: Jeon Y, Lee JT.
Cell 2011-07-08
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X-chromosome epigenetic reprogramming in pluripotent stem cells via noncoding genes.

Authors: Authors: Kim DH, Jeon Y, Anguera MC, Lee JT.
Semin Cell Dev Biol 2011-06-01
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