Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Genetics and disease of ventricular muscle.
Authors: Authors: Fatkin D, Seidman CE, Seidman JG.
Cold Spring Harb Perspect Med
View full abstract on Pubmed
The role of mutant protein level in autosomal recessive catecholamine dependent polymorphic ventricular tachycardia (CPVT2).
Authors: Authors: Katz G, Shainberg A, Hochhauser E, Kurtzwald-Josefson E, Issac A, El-Ani D, Aravot D, Afek A, Seidman JG, Seidman CE, Eldar M, Arad M.
Biochem Pharmacol
View full abstract on Pubmed
Assessing the phenotypic effects in the general population of rare variants in genes for a dominant Mendelian form of diabetes.
Authors: Authors: Flannick J, Beer NL, Bick AG, Agarwala V, Molnes J, Gupta N, Burtt NP, Florez JC, Meigs JB, Taylor H, Lyssenko V, Irgens H, Fox E, Burslem F, Johansson S, Brosnan MJ, Trimmer JK, Newton-Cheh C, Tuomi T, Molven A, Wilson JG, O'Donnell CJ, Kathiresan S, Hirschhorn JN, Njølstad PR, Rolph T, Seidman JG, Gabriel S, Cox DR, Seidman CE, Groop L, Altshuler D.
Nat Genet
View full abstract on Pubmed
Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.
Authors: Authors: Jiang J, Wakimoto H, Seidman JG, Seidman CE.
Science
View full abstract on Pubmed
The Cancer Genome Atlas Pan-Cancer analysis project.
Authors: Authors: Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM.
Nat Genet
View full abstract on Pubmed
HOXA2 haploinsufficiency in dominant bilateral microtia and hearing loss.
Authors: Authors: Brown KK, Viana LM, Helwig CC, Artunduaga MA, Quintanilla-Dieck L, Jarrin P, Osorno G, McDonough B, DePalma SR, Eavey RD, Seidman JG, Seidman CE.
Hum Mutat
View full abstract on Pubmed
An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.
Authors: Authors: Ayturk UM, Jacobsen CM, Christodoulou DC, Gorham J, Seidman JG, Seidman CE, Robling AG, Warman ML.
J Bone Miner Res
View full abstract on Pubmed
Quantification of microRNA expression with next-generation sequencing.
Authors: Authors: Eminaga S, Christodoulou DC, Vigneault F, Church GM, Seidman JG.
Curr Protoc Mol Biol
View full abstract on Pubmed
De novo mutations in histone-modifying genes in congenital heart disease.
Authors: Authors: Zaidi S, Choi M, Wakimoto H, Ma L, Jiang J, Overton JD, Romano-Adesman A, Bjornson RD, Breitbart RE, Brown KK, Carriero NJ, Cheung YH, Deanfield J, DePalma S, Fakhro KA, Glessner J, Hakonarson H, Italia MJ, Kaltman JR, Kaski J, Kim R, Kline JK, Lee T, Leipzig J, Lopez A, Mane SM, Mitchell LE, Newburger JW, Parfenov M, Pe'er I, Porter G, Roberts AE, Sachidanandam R, Sanders SJ, Seiden HS, State MW, Subramanian S, Tikhonova IR, Wang W, Warburton D, White PS, Williams IA, Zhao H, Seidman JG, Brueckner M, Chung WK, Gelb BD, Goldmuntz E, Seidman CE, Lifton RP.
Nature
View full abstract on Pubmed
Spatial transcriptional profile of the chick and mouse endocardial cushions identify novel regulators of endocardial EMT in vitro.
Authors: Authors: DeLaughter DM, Christodoulou DC, Robinson JY, Seidman CE, Baldwin HS, Seidman JG, Barnett JV.
J Mol Cell Cardiol
View full abstract on Pubmed