
Jonathan G. Seidman, Ph.D.
Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.
Authors: Authors: Yoshioka J, Chutkow WA, Lee S, Kim JB, Yan J, Tian R, Lindsey ML, Feener EP, Seidman CE, Seidman JG, Lee RT.
J Clin Invest
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J Clin Invest
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Stable gene targeting in human cells using single-strand oligonucleotides with modified bases.
Authors: Authors: Rios X, Briggs AW, Christodoulou D, Gorham JM, Seidman JG, Church GM.
PLoS One
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PLoS One
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Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.
Authors: Authors: Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA.
Cell Metab
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Cell Metab
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Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.
Authors: Authors: LeMaire SA, McDonald ML, Guo DC, Russell L, Miller CC, Johnson RJ, Bekheirnia MR, Franco LM, Nguyen M, Pyeritz RE, Bavaria JE, Devereux R, Maslen C, Holmes KW, Eagle K, Body SC, Seidman C, Seidman JG, Isselbacher EM, Bray M, Coselli JS, Estrera AL, Safi HJ, Belmont JW, Leal SM, Milewicz DM.
Nat Genet
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Nat Genet
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Barcoding bias in high-throughput multiplex sequencing of miRNA.
Authors: Authors: Alon S, Vigneault F, Eminaga S, Christodoulou DC, Seidman JG, Church GM, Eisenberg E.
Genome Res
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Genome Res
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Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.
Authors: Authors: Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz TW.
Physiol Genomics
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Physiol Genomics
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Loss-of-function mutations in PTPN11 cause metachondromatosis, but not Ollier disease or Maffucci syndrome.
Authors: Authors: Bowen ME, Boyden ED, Holm IA, Campos-Xavier B, Bonafé L, Superti-Furga A, Ikegawa S, Cormier-Daire V, Bovée JV, Pansuriya TC, de Sousa SB, Savarirayan R, Andreucci E, Vikkula M, Garavelli L, Pottinger C, Ogino T, Sakai A, Regazzoni BM, Wuyts W, Sangiorgi L, Pedrini E, Zhu M, Kozakewich HP, Kasser JR, Seidman JG, Kurek KC, Warman ML.
PLoS Genet
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PLoS Genet
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Construction of normalized RNA-seq libraries for next-generation sequencing using the crab duplex-specific nuclease.
Authors: Authors: Christodoulou DC, Gorham JM, Herman DS, Seidman JG.
Curr Protoc Mol Biol
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Curr Protoc Mol Biol
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Identifying sarcomere gene mutations in hypertrophic cardiomyopathy: a personal history.
Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]
Authors: Authors: Moskowitz IP, Wang J, Peterson MA, Pu WT, Mackinnon AC, Oxburgh L, Chu GC, Sarkar M, Berul C, Smoot L, Robertson EJ, Schwartz R, Seidman JG, Seidman CE.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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