Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
Polycomb repressive complex 2 regulates normal development of the mouse heart.
Authors: Authors: He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT.
Circ Res
View full abstract on Pubmed
CD36 overexpression predisposes to arrhythmias but reduces infarct size in spontaneously hypertensive rats: gene expression profile analysis.
Authors: Authors: Neckár J, Šilhavy J, Zídek V, Landa V, Mlejnek P, Šimáková M, Seidman JG, Seidman C, Kazdová L, Klevstig M, Novák F, Vecka M, Papoušek F, Houštek J, Drahota Z, Kurtz TW, Kolár F, Pravenec M.
Physiol Genomics
View full abstract on Pubmed
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.
Authors: Authors: Delgado-Olguín P, Huang Y, Li X, Christodoulou D, Seidman CE, Seidman JG, Tarakhovsky A, Bruneau BG.
Nat Genet
View full abstract on Pubmed
Brazilian urban population genetic structure reveals a high degree of admixture.
Authors: Authors: Giolo SR, Soler JM, Greenway SC, Almeida MA, de Andrade M, Seidman JG, Seidman CE, Krieger JE, Pereira AC.
Eur J Hum Genet
View full abstract on Pubmed
Deletion of thioredoxin-interacting protein in mice impairs mitochondrial function but protects the myocardium from ischemia-reperfusion injury.
Authors: Authors: Yoshioka J, Chutkow WA, Lee S, Kim JB, Yan J, Tian R, Lindsey ML, Feener EP, Seidman CE, Seidman JG, Lee RT.
J Clin Invest
View full abstract on Pubmed
Stable gene targeting in human cells using single-strand oligonucleotides with modified bases.
Authors: Authors: Rios X, Briggs AW, Christodoulou D, Gorham JM, Seidman JG, Church GM.
PLoS One
View full abstract on Pubmed
Heterozygosity for a loss-of-function mutation in GALNT2 improves plasma triglyceride clearance in man.
Authors: Authors: Holleboom AG, Karlsson H, Lin RS, Beres TM, Sierts JA, Herman DS, Stroes ES, Aerts JM, Kastelein JJ, Motazacker MM, Dallinga-Thie GM, Levels JH, Zwinderman AH, Seidman JG, Seidman CE, Ljunggren S, Lefeber DJ, Morava E, Wevers RA, Fritz TA, Tabak LA, Lindahl M, Hovingh GK, Kuivenhoven JA.
Cell Metab
View full abstract on Pubmed
Genome-wide association study identifies a susceptibility locus for thoracic aortic aneurysms and aortic dissections spanning FBN1 at 15q21.1.
Authors: Authors: LeMaire SA, McDonald ML, Guo DC, Russell L, Miller CC, Johnson RJ, Bekheirnia MR, Franco LM, Nguyen M, Pyeritz RE, Bavaria JE, Devereux R, Maslen C, Holmes KW, Eagle K, Body SC, Seidman C, Seidman JG, Isselbacher EM, Bray M, Coselli JS, Estrera AL, Safi HJ, Belmont JW, Leal SM, Milewicz DM.
Nat Genet
View full abstract on Pubmed
Barcoding bias in high-throughput multiplex sequencing of miRNA.
Authors: Authors: Alon S, Vigneault F, Eminaga S, Christodoulou DC, Seidman JG, Church GM, Eisenberg E.
Genome Res
View full abstract on Pubmed
Age-related autocrine diabetogenic effects of transgenic resistin in spontaneously hypertensive rats: gene expression profile analysis.
Authors: Authors: Pravenec M, Zídek V, Landa V, Simáková M, Mlejnek P, Silhavy J, Maxová M, Kazdová L, Seidman JG, Seidman CE, Eminaga S, Gorham J, Wang J, Kurtz TW.
Physiol Genomics
View full abstract on Pubmed