Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy.
Authors: Authors: Saltzman AJ, Mancini-DiNardo D, Li C, Chung WK, Ho CY, Hurst S, Wynn J, Care M, Hamilton RM, Seidman GW, Gorham J, McDonough B, Sparks E, Seidman JG, Seidman CE, Rehm HL.
Circ Res
View full abstract on Pubmed
A novel custom resequencing array for dilated cardiomyopathy.
Authors: Authors: Zimmerman RS, Cox S, Lakdawala NK, Cirino A, Mancini-DiNardo D, Clark E, Leon A, Duffy E, White E, Baxter S, Alaamery M, Farwell L, Weiss S, Seidman CE, Seidman JG, Ho CY, Rehm HL, Funke BH.
Genet Med
View full abstract on Pubmed
Genetics of hypertrophic cardiomyopathy.
Authors: Authors: Konno T, Chang S, Seidman JG, Seidman CE.
Curr Opin Cardiol
View full abstract on Pubmed
Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy.
Authors: Authors: Wang L, Seidman JG, Seidman CE.
Ann Intern Med
View full abstract on Pubmed
Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.
Authors: Authors: Lakdawala NK, Dellefave L, Redwood CS, Sparks E, Cirino AL, Depalma S, Colan SD, Funke B, Zimmerman RS, Robinson P, Watkins H, Seidman CE, Seidman JG, McNally EM, Ho CY.
J Am Coll Cardiol
View full abstract on Pubmed
Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2.
Authors: Authors: Liu X, Han D, Li J, Han B, Ouyang X, Cheng J, Li X, Jin Z, Wang Y, Bitner-Glindzicz M, Kong X, Xu H, Kantardzhieva A, Eavey RD, Seidman CE, Seidman JG, Du LL, Chen ZY, Dai P, Teng M, Yan D, Yuan H.
Am J Hum Genet
View full abstract on Pubmed
Ca2+ dysregulation in Ryr1(I4895T/wt) mice causes congenital myopathy with progressive formation of minicores, cores, and nemaline rods.
Authors: Authors: Zvaritch E, Kraeva N, Bombardier E, McCloy RA, Depreux F, Holmyard D, Kraev A, Seidman CE, Seidman JG, Tupling AR, MacLennan DH.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
[Using molecular genetics to guide the diagnosis and treatment of hypertrophic cardiomyopathy].
Authors: Authors: Wang LB, Seidman JG, Seidman CE.
Zhonghua Xin Xue Guan Bing Za Zhi
View full abstract on Pubmed
Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.
Authors: Authors: Body SC, Collard CD, Shernan SK, Fox AA, Liu KY, Ritchie MD, Perry TE, Muehlschlegel JD, Aranki S, Donahue BS, Pretorius M, Estrada JC, Ellinor PT, Newton-Cheh C, Seidman CE, Seidman JG, Herman DS, Lichtner P, Meitinger T, Pfeufer A, Kääb S, Brown NJ, Roden DM, Darbar D.
Circ Cardiovasc Genet
View full abstract on Pubmed
A classic twin study of external ear malformations, including microtia.
Authors: Authors: Artunduaga MA, Quintanilla-Dieck Mde L, Greenway S, Betensky R, Nicolau Y, Hamdan U, Jarrin P, Osorno G, Brent B, Eavey R, Seidman C, Seidman JG.
N Engl J Med
View full abstract on Pubmed