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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Genome-wide identification of mouse congenital heart disease loci.
Authors: Authors: Kamp A, Peterson MA, Svenson KL, Bjork BC, Hentges KE, Rajapaksha TW, Moran J, Justice MJ, Seidman JG, Seidman CE, Moskowitz IP, Beier DR.
Hum Mol Genet
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Myocardial fibrosis as an early manifestation of hypertrophic cardiomyopathy.
Authors: Authors: Ho CY, López B, Coelho-Filho OR, Lakdawala NK, Cirino AL, Jarolim P, Kwong R, González A, Colan SD, Seidman JG, Díez J, Seidman CE.
N Engl J Med
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Sarcomere gene mutations in hypertrophy and heart failure.
Authors: Authors: Morita H, Nagai R, Seidman JG, Seidman CE.
J Cardiovasc Transl Res
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Dissecting spatio-temporal protein networks driving human heart development and related disorders.
Authors: Authors: Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA.
Mol Syst Biol
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Short communication: the cardiac myosin binding protein C Arg502Trp mutation: a common cause of hypertrophic cardiomyopathy.
Authors: Authors: Saltzman AJ, Mancini-DiNardo D, Li C, Chung WK, Ho CY, Hurst S, Wynn J, Care M, Hamilton RM, Seidman GW, Gorham J, McDonough B, Sparks E, Seidman JG, Seidman CE, Rehm HL.
Circ Res
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A novel custom resequencing array for dilated cardiomyopathy.
Authors: Authors: Zimmerman RS, Cox S, Lakdawala NK, Cirino A, Mancini-DiNardo D, Clark E, Leon A, Duffy E, White E, Baxter S, Alaamery M, Farwell L, Weiss S, Seidman CE, Seidman JG, Ho CY, Rehm HL, Funke BH.
Genet Med
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Genetics of hypertrophic cardiomyopathy.
Authors: Authors: Konno T, Chang S, Seidman JG, Seidman CE.
Curr Opin Cardiol
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Narrative review: harnessing molecular genetics for the diagnosis and management of hypertrophic cardiomyopathy.
Authors: Authors: Wang L, Seidman JG, Seidman CE.
Ann Intern Med
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Familial dilated cardiomyopathy caused by an alpha-tropomyosin mutation: the distinctive natural history of sarcomeric dilated cardiomyopathy.
Authors: Authors: Lakdawala NK, Dellefave L, Redwood CS, Sparks E, Cirino AL, Depalma S, Colan SD, Funke B, Zimmerman RS, Robinson P, Watkins H, Seidman CE, Seidman JG, McNally EM, Ho CY.
J Am Coll Cardiol
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Loss-of-function mutations in the PRPS1 gene cause a type of nonsyndromic X-linked sensorineural deafness, DFN2.
Authors: Authors: Liu X, Han D, Li J, Han B, Ouyang X, Cheng J, Li X, Jin Z, Wang Y, Bitner-Glindzicz M, Kong X, Xu H, Kantardzhieva A, Eavey RD, Seidman CE, Seidman JG, Du LL, Chen ZY, Dai P, Teng M, Yan D, Yuan H.
Am J Hum Genet
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