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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.
Authors: Authors: Palmer BM, Noguchi T, Wang Y, Heim JR, Alpert NR, Burgon PG, Seidman CE, Seidman JG, Maughan DW, LeWinter MM.
Circ Res
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Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening.
Authors: Authors: Palmer BM, Georgakopoulos D, Janssen PM, Wang Y, Alpert NR, Belardi DF, Harris SP, Moss RL, Burgon PG, Seidman CE, Seidman JG, Maughan DW, Kass DA.
Circ Res
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A novel missense mutation in the paired domain of PAX9 causes non-syndromic oligodontia.
Authors: Authors: Jumlongras D, Lin JY, Chapra A, Seidman CE, Seidman JG, Maas RL, Olsen BR.
Hum Genet
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Electrophysiologic characterization and postnatal development of ventricular pre-excitation in a mouse model of cardiac hypertrophy and Wolff-Parkinson-White syndrome.
Authors: Authors: Patel VV, Arad M, Moskowitz IP, Maguire CT, Branco D, Seidman JG, Seidman CE, Berul CI.
J Am Coll Cardiol
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Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.
Authors: Authors: Schmitt JP, Semsarian C, Arad M, Gannon J, Ahmad F, Duffy C, Lee RT, Seidman CE, Seidman JG.
Circulation
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Adult Hallervorden-Spatz syndrome simulating amyotrophic lateral sclerosis.
Authors: Authors: Vasconcelos OM, Harter DH, Duffy C, McDonough B, Seidman JG, Seidman CE, Campbell WW.
Muscle Nerve
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Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.
Authors: Authors: Arad M, Moskowitz IP, Patel VV, Ahmad F, Perez-Atayde AR, Sawyer DB, Walter M, Li GH, Burgon PG, Maguire CT, Stapleton D, Schmitt JP, Guo XX, Pizard A, Kupershmidt S, Roden DM, Berul CI, Seidman CE, Seidman JG.
Circulation
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Tbx5 is required for forelimb bud formation and continued outgrowth.
Authors: Authors: Rallis C, Bruneau BG, Del Buono J, Seidman CE, Seidman JG, Nissim S, Tabin CJ, Logan MP.
Development
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Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
Authors: Authors: Song Q, Schmidt AG, Hahn HS, Carr AN, Frank B, Pater L, Gerst M, Young K, Hoit BD, McConnell BK, Haghighi K, Seidman CE, Seidman JG, Dorn GW, Kranias EG.
J Clin Invest
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IL-12 is required for differentiation of pathogenic CD8+ T cell effectors that cause myocarditis.
Authors: Authors: Grabie N, Delfs MW, Westrich JR, Love VA, Stavrakis G, Ahmad F, Seidman CE, Seidman JG, Lichtman AH.
J Clin Invest
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