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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Sarcomere protein gene mutations and inherited heart disease: a beta-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure.
Authors: Authors: Kamisago M, Schmitt JP, McNamara D, Seidman C, Seidman JG.
Novartis Found Symp
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Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
Authors: Authors: Wolf CM, Moskowitz IP, Arno S, Branco DM, Semsarian C, Bernstein SA, Peterson M, Maida M, Morley GE, Fishman G, Berul CI, Seidman CE, Seidman JG.
Proc Natl Acad Sci U S A
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Cardiac myosin-binding protein-C phosphorylation and cardiac function.
Authors: Authors: Sadayappan S, Gulick J, Osinska H, Martin LA, Hahn HS, Dorn GW, Klevitsky R, Seidman CE, Seidman JG, Robbins J.
Circ Res
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Increased alpha2 subunit-associated AMPK activity and PRKAG2 cardiomyopathy.
Authors: Authors: Ahmad F, Arad M, Musi N, He H, Wolf C, Branco D, Perez-Atayde AR, Stapleton D, Bali D, Xing Y, Tian R, Goodyear LJ, Berul CI, Ingwall JS, Seidman CE, Seidman JG.
Circulation
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Gene mutations in apical hypertrophic cardiomyopathy.
Authors: Authors: Arad M, Penas-Lado M, Monserrat L, Maron BJ, Sherrid M, Ho CY, Barr S, Karim A, Olson TM, Kamisago M, Seidman JG, Seidman CE.
Circulation
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Compound and double mutations in patients with hypertrophic cardiomyopathy: implications for genetic testing and counselling.
Authors: Authors: Ingles J, Doolan A, Chiu C, Seidman J, Seidman C, Semsarian C.
J Med Genet
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N488I mutation of the gamma2-subunit results in bidirectional changes in AMP-activated protein kinase activity.
Authors: Authors: Zou L, Shen M, Arad M, He H, Løfgren B, Ingwall JS, Seidman CE, Seidman JG, Tian R.
Circ Res
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Connexin 40, a target of transcription factor Tbx5, patterns wrist, digits, and sternum.
Authors: Authors: Pizard A, Burgon PG, Paul DL, Bruneau BG, Seidman CE, Seidman JG.
Mol Cell Biol
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A novel COL1A1 mutation in infantile cortical hyperostosis (Caffey disease) expands the spectrum of collagen-related disorders.
Authors: Authors: Gensure RC, Mäkitie O, Barclay C, Chan C, Depalma SR, Bastepe M, Abuzahra H, Couper R, Mundlos S, Sillence D, Ala Kokko L, Seidman JG, Cole WG, Jüppner H.
J Clin Invest
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Functional role of AMP-activated protein kinase in the heart during exercise.
Authors: Authors: Musi N, Hirshman MF, Arad M, Xing Y, Fujii N, Pomerleau J, Ahmad F, Berul CI, Seidman JG, Tian R, Goodyear LJ.
FEBS Lett
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