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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Mutations in the cardiac transcription factor NKX2.5 affect diverse cardiac developmental pathways.
Authors: Authors: Benson DW, Silberbach GM, Kavanaugh-McHugh A, Cottrill C, Zhang Y, Riggs S, Smalls O, Johnson MC, Watson MS, Seidman JG, Seidman CE, Plowden J, Kugler JD.
J Clin Invest
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Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.
Authors: Authors: McConnell BK, Jones KA, Fatkin D, Arroyo LH, Lee RT, Aristizabal O, Turnbull DH, Georgakopoulos D, Kass D, Bond M, Niimura H, Schoen FJ, Conner D, Fischman DA, Seidman CE, Seidman JG, Fischman DH.
J Clin Invest
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Altered regulatory function of two familial hypertrophic cardiomyopathy troponin T mutants.
Authors: Authors: Mukherjea P, Tong L, Seidman JG, Seidman CE, Hitchcock-DeGregori SE.
Biochemistry
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Hereditary postlingual sensorineural hearing loss mapping to chromosome Xq21.
Authors: Authors: Manolis EN, Eavey RD, Sangwatanaroj S, Halpin C, Rosenbaum S, Watkins H, Jarcho J, Seidman CE, Seidman JG.
Am J Otol
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Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome.
Authors: Authors: Bruneau BG, Logan M, Davis N, Levi T, Tabin CJ, Seidman JG, Seidman CE.
Dev Biol
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Familial hypertrophic cardiomyopathy and atrial fibrillation caused by Arg663His beta-cardiac myosin heavy chain mutation.
Authors: Authors: Gruver EJ, Fatkin D, Dodds GA, Kisslo J, Maron BJ, Seidman JG, Seidman CE.
Am J Cardiol
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The spectrum of mutations in TBX3: Genotype/Phenotype relationship in ulnar-mammary syndrome.
Authors: Authors: Bamshad M, Le T, Watkins WS, Dixon ME, Kramer BE, Roeder AD, Carey JC, Root S, Schinzel A, Van Maldergem L, Gardner RJ, Lin RC, Seidman CE, Seidman JG, Wallerstein R, Moran E, Sutphen R, Campbell CE, Jorde LB.
Am J Hum Genet
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QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice.
Authors: Authors: Bevilacqua LM, Maguire CT, Seidman JG, Seidman CE, Berul CI.
Pediatr Res
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Electrophysiologic characteristics of accessory atrioventricular connections in an inherited form of Wolff-Parkinson-White syndrome.
Authors: Authors: Mehdirad AA, Fatkin D, DiMarco JP, MacRae CA, Wase A, Seidman JG, Seidman CE, Benson DW.
J Cardiovasc Electrophysiol
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An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.
Authors: Authors: Kim SJ, Iizuka K, Kelly RA, Geng YJ, Bishop SP, Yang G, Kudej A, McConnell BK, Seidman CE, Seidman JG, Vatner SF.
Am J Physiol
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