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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus.
Authors: Authors: Zhuo M, Zhang W, Son H, Mansuy I, Sobel RA, Seidman J, Kandel ER.
Proc Natl Acad Sci U S A
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Long-term follow-up of chimpanzees inoculated with the first infectious clone for hepatitis C virus.
Authors: Authors: Major ME, Mihalik K, Fernandez J, Seidman J, Kleiner D, Kolykhalov AA, Rice CM, Feinstone SM.
J Virol
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Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations.
Authors: Authors: Basson CT, Huang T, Lin RC, Bachinsky DR, Weremowicz S, Vaglio A, Bruzzone R, Quadrelli R, Lerone M, Romeo G, Silengo M, Pereira A, Krieger J, Mesquita SF, Kamisago M, Morton CC, Pierpont ME, Müller CW, Seidman JG, Seidman CE.
Proc Natl Acad Sci U S A
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Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Authors: Authors: Blanchard E, Seidman C, Seidman JG, LeWinter M, Maughan D.
Circ Res
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Familial dilated cardiomyopathy locus maps to chromosome 2q31.
Authors: Authors: Siu BL, Niimura H, Osborne JA, Fatkin D, MacRae C, Solomon S, Benson DW, Seidman JG, Seidman CE.
Circulation
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The pathogenesis of familial hypertrophic cardiomyopathy: early and evolving effects from an alpha-cardiac myosin heavy chain missense mutation.
Authors: Authors: Georgakopoulos D, Christe ME, Giewat M, Seidman CM, Seidman JG, Kass DA.
Nat Med
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Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy.
Authors: Authors: Gao WD, Pérez NG, Seidman CE, Seidman JG, Marbán E.
J Clin Invest
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Regulation of chamber-specific gene expression in the developing heart by Irx4.
Authors: Authors: Bao ZZ, Bruneau BG, Seidman JG, Seidman CE, Cepko CL.
Science
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QTL influencing autoimmune diabetes and encephalomyelitis map to a 0.15-cM region containing Il2.
Authors: Authors: Encinas JA, Wicker LS, Peterson LB, Mukasa A, Teuscher C, Sobel R, Weiner HL, Seidman CE, Seidman JG, Kuchroo VK.
Nat Genet
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Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the alpha cardiac myosin heavy chain gene.
Authors: Authors: Fatkin D, Christe ME, Aristizabal O, McConnell BK, Srinivasan S, Schoen FJ, Seidman CE, Turnbull DH, Seidman JG.
J Clin Invest
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