Jonathan Seidman headshot

Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
617-432-7830
Seidman Lab Website
Effects of two familial hypertrophic cardiomyopathy-causing mutations on alpha-tropomyosin structure and function.
Authors: Authors: Golitsina N, An Y, Greenfield NJ, Thierfelder L, Iizuka K, Seidman JG, Seidman CE, Lehrer SS, Hitchcock-DeGregori SE.
Biochemistry
View full abstract on Pubmed
Cao-sensing receptor (CaR)-mediated activation of K+ channels is blunted in CaR gene-deficient mouse neurons.
Authors: Authors: Vassilev PM, Ho-Pao CL, Kanazirska MP, Ye C, Hong K, Seidman CE, Seidman JG, Brown EM.
Neuroreport
View full abstract on Pubmed
Various types of hereditary inclusion body myopathies map to chromosome 9p1-q1.
Authors: Authors: Argov Z, Tiram E, Eisenberg I, Sadeh M, Seidman CE, Seidman JG, Karpati G, Mitrani-Rosenbaum S.
Ann Neurol
View full abstract on Pubmed
Cytoskeletal changes in the brains of mice lacking calcineurin A alpha.
Authors: Authors: Kayyali US, Zhang W, Yee AG, Seidman JG, Potter H.
J Neurochem
View full abstract on Pubmed
Clinical features of hypertrophic cardiomyopathy caused by mutation of a "hot spot" in the alpha-tropomyosin gene.
Authors: Authors: Coviello DA, Maron BJ, Spirito P, Watkins H, Vosberg HP, Thierfelder L, Schoen FJ, Seidman JG, Seidman CE.
J Am Coll Cardiol
View full abstract on Pubmed
Amyloid-beta proteins activate Ca(2+)-permeable channels through calcium-sensing receptors.
Authors: Authors: Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Rogers K, Seidman CE, Seidman JG, Brown EM, Vassilev PM.
J Neurosci Res
View full abstract on Pubmed
Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.
Authors: Authors: Berul CI, Christe ME, Aronovitz MJ, Seidman CE, Seidman JG, Mendelsohn ME.
J Clin Invest
View full abstract on Pubmed
Genetic heterogeneity evidenced by low incidence of KAL-1 gene mutations in sporadic cases of gonadotropin-releasing hormone deficiency.
Authors: Authors: Georgopoulos NA, Pralong FP, Seidman CE, Seidman JG, Crowley WF, Vallejo M.
J Clin Endocrinol Metab
View full abstract on Pubmed
Deficient cation channel regulation in neurons from mice with targeted disruption of the extracellular Ca2+-sensing receptor gene.
Authors: Authors: Ye C, Ho-Pao CL, Kanazirska M, Quinn S, Seidman CE, Seidman JG, Brown EM, Vassilev PM.
Brain Res Bull
View full abstract on Pubmed
Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome.
Authors: Authors: Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman JG, Seidman CE.
Nat Genet
View full abstract on Pubmed