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Jonathan G. Seidman, Ph.D.

Henrietta B. and Frederick H. Bugher Foundation Professor of Genetics, Harvard Medical School
cruzi Infection in hiPSC-Derived Cardiomyocytes From Chagas Disease Patients With and Without Chronic Cardiomyopathy
Authors: Authors: Different Transcriptomic Response to T
Front Cell Infect Microbiol
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Novel and Annotated Long Noncoding RNAs Associated with Ischemia in the Human Heart.
Authors: Authors: Ward Z, Schmeier S, Saddic L, Sigurdsson MI, Cameron VA, Pearson J, Miller A, Morley-Bunker A, Gorham J, Seidman JG, Moravec CS, Sweet WE, Aranki SF, Body S, Muehlschlegel JD, Pilbrow AP.
Int J Mol Sci
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Plakophilin-2 truncating variants impair cardiac contractility by disrupting sarcomere stability and organization.
Authors: Authors: Zhang K, Cloonan PE, Sundaram S, Liu F, Das SL, Ewoldt JK, Bays JL, Tomp S, Toepfer CN, Marsiglia JDC, Gorham J, Reichart D, Eyckmans J, Seidman JG, Seidman CE, Chen CS.
Sci Adv
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LAMP2 Cardiomyopathy: Consequences of Impaired Autophagy in the Heart.
Authors: Authors: Alcalai R, Arad M, Wakimoto H, Yadin D, Gorham J, Wang L, Burns E, Maron BJ, Roberts WC, Konno T, Conner DA, Perez-Atayde AR, Seidman JG, Seidman CE.
J Am Heart Assoc
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Contribution of Noncanonical Splice Variants to TTN Truncating Variants Cardiomyopathy.
Authors: Authors: Patel PN, Ito K, Willcox JAL, Haghighi A, Jang MY, Gorham JM, DePalma SR, Lam L, McDonough B, Johnson R, Lakdawala NK, Roberts A, Barton PJR, Cook SA, Fatkin D, Seidman CE, Seidman JG.
Circ Genom Precis Med
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Filamin C Cardiomyopathy Variants Cause Protein and Lysosome Accumulation.
Authors: Authors: Agarwal R, Paulo J, Toepfer CN, Ewoldt JK, Sundaram S, Chopra A, Zhang Q, Gorham J, DePalma S, Chen CS, Gygi S, Seidman CE, Seidman JG.
Circ Res
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Genomic frontiers in congenital heart disease.
Authors: Authors: Morton SU, Quiat D, Seidman JG, Seidman CE.
Nat Rev Cardiol
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CalTrack: High-Throughput Automated Calcium Transient Analysis in Cardiomyocytes.
Authors: Authors: Psaras Y, Margara F, Cicconet M, Sparrow AJ, Repetti GG, Schmid M, Steeples V, Wilcox JAL, Bueno-Orovio A, Redwood CS, Watkins HC, Robinson P, Rodriguez B, Seidman JG, Seidman CE, Toepfer CN.
Circ Res
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Genetic and Phenotypic Landscape of Peripartum Cardiomyopathy.
Authors: Authors: Goli R, Li J, Brandimarto J, Levine LD, Riis V, McAfee Q, DePalma S, Haghighi A, Seidman JG, Seidman CE, Jacoby D, Macones G, Judge DP, Rana S, Margulies KB, Cappola TP, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Alexis JD, Boehmer J, Kamiya C, Gustafsson F, Damm P, Ersbøll AS, Goland S, Hilfiker-Kleiner D, McNamara DM, Arany Z.
Circulation
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Isolation of Nuclei from Mammalian Cells and Tissues for Single-Nucleus Molecular Profiling.
Authors: Authors: Nadelmann ER, Gorham JM, Reichart D, Delaughter DM, Wakimoto H, Lindberg EL, Litvinukova M, Maatz H, Curran JJ, Ischiu Gutierrez D, Hübner N, Seidman CE, Seidman JG.
Curr Protoc
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