Konrad Hochedlinger

Konrad Hochedlinger, Ph.D.

Professor of Genetics, Massachusetts General Hospital
617-643-2075
Konrad Hochedlinger Website
Optimal-Transport Analysis of Single-Cell Gene Expression Identifies Developmental Trajectories in Reprogramming.
Authors: Authors: Schiebinger G, Shu J, Tabaka M, Cleary B, Subramanian V, Solomon A, Gould J, Liu S, Lin S, Berube P, Lee L, Chen J, Brumbaugh J, Rigollet P, Hochedlinger K, Jaenisch R, Regev A, Lander ES.
Cell
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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Authors: Authors: Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T.
Cell Stem Cell
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Novel Roles for SUMOylation in Cellular Plasticity.
Authors: Authors: Di Stefano B, Hochedlinger K.
Trends Cell Biol
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Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.
Authors: Authors: Sardina JL, Collombet S, Tian TV, Gómez A, Di Stefano B, Berenguer C, Brumbaugh J, Stadhouders R, Segura-Morales C, Gut M, Gut IG, Heath S, Aranda S, Di Croce L, Hochedlinger K, Thieffry D, Graf T.
Cell Stem Cell
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Reduced MEK inhibition preserves genomic stability in naive human embryonic stem cells.
Authors: Authors: Di Stefano B, Ueda M, Sabri S, Brumbaugh J, Huebner AJ, Sahakyan A, Clement K, Clowers KJ, Erickson AR, Shioda K, Gygi SP, Gu H, Shioda T, Meissner A, Takashima Y, Plath K, Hochedlinger K.
Nat Methods
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Prospective Isolation of Poised iPSC Intermediates Reveals Principles of Cellular Reprogramming.
Authors: Authors: Schwarz BA, Cetinbas M, Clement K, Walsh RM, Cheloufi S, Gu H, Langkabel J, Kamiya A, Schorle H, Meissner A, Sadreyev RI, Hochedlinger K.
Cell Stem Cell
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An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition.
Authors: Authors: Du P, Pirouz M, Choi J, Huebner AJ, Clement K, Meissner A, Hochedlinger K, Gregory RI.
Cell Stem Cell
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Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.
Authors: Authors: Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K.
Stem Cell Reports
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Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
Authors: Authors: Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K.
Cell
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Nudt21 Controls Cell Fate by Connecting Alternative Polyadenylation to Chromatin Signaling.
Authors: Authors: Brumbaugh J, Di Stefano B, Wang X, Borkent M, Forouzmand E, Clowers KJ, Ji F, Schwarz BA, Kalocsay M, Elledge SJ, Chen Y, Sadreyev RI, Gygi SP, Hu G, Shi Y, Hochedlinger K.
Cell
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