Luke H Chao

Luke H Chao, Ph.D.

Assistant Professor of Genetics, Harvard Medical School

617-724-2323

Chao Lab Website

Publications

Click editing enables programmable genome writing using DNA polymerases and HUH endonucleases.

Authors: Authors: Ferreira da Silva J, Tou CJ, King EM, Eller ML, Rufino-Ramos D, Ma L, Cromwell CR, Metovic J, Benning FMC, Chao LH, Eichler FS, Kleinstiver BP.
Nat Biotechnol 2024-07-22
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Ancestral sequence reconstruction of Mic60 reveals a residue signature supporting respiration in yeast.

Authors: Authors: Benning FMC, Bell TA, Nguyen TH, Syau D, Connell LB, daCosta CJB, Chao LH.
bioRxiv 2024-04-29
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In situ architecture of Opa1-dependent mitochondrial cristae remodeling.

Authors: Authors: Fry MY, Navarro PP, Hakim P, Ananda VY, Qin X, Landoni JC, Rath S, Inde Z, Lugo CM, Luce BE, Ge Y, McDonald JL, Ali I, Ha LL, Kleinstiver BP, Chan DC, Sarosiek KA, Chao LH.
EMBO J 2024-01-15
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Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly.

Authors: Authors: Benning FMC, Jenni S, Garcia CY, Nguyen TH, Zhang X, Chao LH.
Nat Commun 2024-01-04
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Identification of SLC25A46 interaction interfaces with mitochondrial membrane fusogens Mfn2 and Opa1.

Authors: Authors: Boopathy S, Lugo CM, Luce BE, McDonald JL, Hakim P, Ponce J, Ueberheide B, Chao LH.
bioRxiv 2023-12-29
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Cholesterol regulates plasma membrane bending by prominin-family proteins.

Authors: Authors: Bell TA, Luce BE, Hakim P, Dardari H, Ananda VY, Nguyen TH, Monshizadeh A, Chao LH.
bioRxiv 2023-11-10
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Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly.

Authors: Authors: Benning FMC, Jenni S, Garcia CY, Nguyen TH, Zhang X, Chao LH.
bioRxiv 2023-06-15
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In situ architecture of Opa1-dependent mitochondrial cristae remodeling.

Authors: Authors: Fry MY, Navarro PP, Qin X, Inde Z, Ananda VY, Lugo CM, Hakim P, Luce BE, Ge Y, McDonald JL, Ali I, Ha LL, Kleinstiver BP, Chan DC, Sarosiek K, Chao LH.
bioRxiv 2023-02-03
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Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli.

Authors: Authors: Navarro PP, Vettiger A, Ananda VY, Llopis PM, Allolio C, Bernhardt TG, Chao LH.
Nat Microbiol 2022-09-12
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A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis.

Authors: Authors: Abdulaziz EN, Bell TA, Rashid B, Heacock ML, Begic T, Skinner OS, Yaseen MA, Chao LH, Mootha VK, Pierik AJ, Cracan V.
J Biol Chem 2022-06-30
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