Luke Chao headshot

Luke H Chao, Ph.D.

Assistant Professor of Genetics, Harvard Medical School
617-724-2323
Chao Lab Website
Helical reconstruction of VP39 reveals principles for baculovirus nucleocapsid assembly.
Authors: Authors: Benning FMC, Jenni S, Garcia CY, Nguyen TH, Zhang X, Chao LH.
bioRxiv
View full abstract on Pubmed
In situ architecture of Opa1-dependent mitochondrial cristae remodeling.
Authors: Authors: Fry MY, Navarro PP, Qin X, Inde Z, Ananda VY, Lugo CM, Hakim P, Luce BE, Ge Y, McDonald JL, Ali I, Ha LL, Kleinstiver BP, Chan DC, Sarosiek K, Chao LH.
bioRxiv
View full abstract on Pubmed
Cell wall synthesis and remodelling dynamics determine division site architecture and cell shape in Escherichia coli.
Authors: Authors: Navarro PP, Vettiger A, Ananda VY, Llopis PM, Allolio C, Bernhardt TG, Chao LH.
Nat Microbiol
View full abstract on Pubmed
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis.
Authors: Authors: Abdulaziz EN, Bell TA, Rashid B, Heacock ML, Begic T, Skinner OS, Yaseen MA, Chao LH, Mootha VK, Pierik AJ, Cracan V.
J Biol Chem
View full abstract on Pubmed
NNT mediates redox-dependent pigmentation via a UVB- and MITF-independent mechanism.
Authors: Authors: Allouche J, Rachmin I, Adhikari K, Pardo LM, Lee JH, McConnell AM, Kato S, Fan S, Kawakami A, Suita Y, Wakamatsu K, Igras V, Zhang J, Navarro PP, Lugo CM, Noonan HR, Christie KA, Itin K, Mujahid N, Lo JA, Won CH, Evans CL, Weng QY, Wang H, Osseiran S, Lovas A, Németh I, Cozzio A, Navarini AA, Hsiao JJ, Nguyen N, Kemény LV, Iliopoulos O, Berking C, Ruzicka T, Gonzalez-José R, Bortolini MC, Canizales-Quinteros S, Acuna-Alonso V, Gallo C, Poletti G, Bedoya G, Rothhammer F, Ito S, Schiaffino MV, Chao LH, Kleinstiver BP, Tishkoff S, Zon LI, Nijsten T, Ruiz-Linares A, Fisher DE, Roider E.
Cell
View full abstract on Pubmed
Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion.
Authors: Authors: Ge Y, Boopathy S, Nguyen TH, Lugo CM, Chao LH.
Front Mol Biosci
View full abstract on Pubmed
A Model Membrane Platform for Reconstituting Mitochondrial Membrane Dynamics.
Authors: Authors: Ge Y, Boopathy S, Smith A, Chao LH.
J Vis Exp
View full abstract on Pubmed
Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation.
Authors: Authors: Sloutsky R, Dziedzic N, Dunn MJ, Bates RM, Torres-Ocampo AP, Boopathy S, Page B, Weeks JG, Chao LH, Stratton MM.
Sci Signal
View full abstract on Pubmed
Two forms of Opa1 cooperate to complete fusion of the mitochondrial inner-membrane.
Authors: Authors: Ge Y, Shi X, Boopathy S, McDonald J, Smith AW, Chao LH.
Elife
View full abstract on Pubmed
The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation.
Authors: Authors: Tilley DC, Angueyra JM, Eum KS, Kim H, Chao LH, Peng AW, Sack JT.
J Gen Physiol
View full abstract on Pubmed