Marjorie Oettinger headshot
Marjorie Ann Oettinger, Ph.D.
Professor of Genetics
RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.
Authors: Authors: Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA.
Nature
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Nonhomologous end joining and V(D)J recombination require an additional factor.
Authors: Authors: Dai Y, Kysela B, Hanakahi LA, Manolis K, Riballo E, Stumm M, Harville TO, West SC, Oettinger MA, Jeggo PA.
Proc Natl Acad Sci U S A
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DNA sequence and structure requirements for cleavage of V(D)J recombination signal sequences.
Authors: Authors: Cuomo CA, Mundy CL, Oettinger MA.
Mol Cell Biol
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The V(D)J recombination activating gene, RAG-1.
Authors: Authors: Schatz DG, Oettinger MA, Baltimore D.
Cell
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The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.
Authors: Authors: Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W.
Proc Natl Acad Sci U S A
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Lysine-79 of histone H3 is hypomethylated at silenced loci in yeast and mammalian cells: a potential mechanism for position-effect variegation.
Authors: Authors: Ng HH, Ciccone DN, Morshead KB, Oettinger MA, Struhl K.
Proc Natl Acad Sci U S A
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Cutting apart V(D)J recombination.
Authors: Authors: Oettinger MA.
Curr Opin Genet Dev
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Suppressors of Saccharomyces cerevisiae his3 promoter mutations lacking the upstream element.
Authors: Authors: Oettinger MA, Struhl K.
Mol Cell Biol
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A PHD finger motif in the C terminus of RAG2 modulates recombination activity.
Authors: Authors: Elkin SK, Ivanov D, Ewalt M, Ferguson CG, Hyberts SG, Sun ZY, Prestwich GD, Yuan J, Wagner G, Oettinger MA, Gozani OP.
J Biol Chem
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Deletion of the RAG2 C terminus leads to impaired lymphoid development in mice.
Authors: Authors: Akamatsu Y, Monroe R, Dudley DD, Elkin SK, Gartner F, Talukder SR, Takahama Y, Alt FW, Bassing CH, Oettinger MA.
Proc Natl Acad Sci U S A
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