The binding between sclerostin and LRP5 is altered by DKK1 and by high-bone mass LRP5 mutations.
Authors: Authors: Balemans W, Piters E, Cleiren E, Ai M, Van Wesenbeeck L, Warman ML, Van Hul W.
Calcif Tissue Int
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Calcif Tissue Int
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Unique roles of microRNA140 and its host gene WWP2 in cartilage biology.
Authors: Authors: Nakamura Y, He X, Kobayashi T, Yan YL, Postlethwait JH, Warman ML.
J Musculoskelet Neuronal Interact
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J Musculoskelet Neuronal Interact
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Association between friction and wear in diarthrodial joints lacking lubricin.
Authors: Authors: Jay GD, Torres JR, Rhee DK, Helminen HJ, Hytinnen MM, Cha CJ, Elsaid K, Kim KS, Cui Y, Warman ML.
Arthritis Rheum
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Arthritis Rheum
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The CCN family member Wisp3, mutant in progressive pseudorheumatoid dysplasia, modulates BMP and Wnt signaling.
Authors: Authors: Nakamura Y, Weidinger G, Liang JO, Aquilina-Beck A, Tamai K, Moon RT, Warman ML.
J Clin Invest
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J Clin Invest
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The role of lubricin in the mechanical behavior of synovial fluid.
Authors: Authors: Jay GD, Torres JR, Warman ML, Laderer MC, Breuer KS.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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The Wnt co-receptor LRP5 is essential for skeletal mechanotransduction but not for the anabolic bone response to parathyroid hormone treatment.
Authors: Authors: Sawakami K, Robling AG, Ai M, Pitner ND, Liu D, Warden SJ, Li J, Maye P, Rowe DW, Duncan RL, Warman ML, Turner CH.
J Biol Chem
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J Biol Chem
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Heterozygous mutations in natriuretic peptide receptor-B (NPR2) are associated with short stature.
Authors: Authors: Olney RC, Bükülmez H, Bartels CF, Prickett TC, Espiner EA, Potter LR, Warman ML.
J Clin Endocrinol Metab
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J Clin Endocrinol Metab
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Somatic mosaicism in a male with an exon skipping mutation in PDHA1 of the pyruvate dehydrogenase complex results in a milder phenotype.
Authors: Authors: Okajima K, Warman ML, Byrne LC, Kerr DS.
Mol Genet Metab
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Mol Genet Metab
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Hip joint replacement surgery for idiopathic osteoarthritis aggregates in families.
Authors: Authors: Bukulmez H, Matthews AL, Sullivan CM, Chen C, Kraay MJ, Elston RC, Moskowitz RW, Goldberg VM, Warman ML.
Arthritis Res Ther
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Arthritis Res Ther
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Lrp5-independent activation of Wnt signaling by lithium chloride increases bone formation and bone mass in mice.
Authors: Authors: Clément-Lacroix P, Ai M, Morvan F, Roman-Roman S, Vayssière B, Belleville C, Estrera K, Warman ML, Baron R, Rawadi G.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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