Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Metabolic command centers in Drosophila: how the fat body and oenocytes orchestrate immunity, reproduction, and aging.
Cholinergic signaling modulates intestinal pathophysiology in a Drosophila model of cystic fibrosis.
Authors: Authors: Lane EA, Petsakou A, Liu Y, Chen W, Qadiri M, Hu Y, Perrimon N.
PLoS Genet
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PLoS Genet
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Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels.
Authors: Authors: Moon SJ, Hu Y, Dzieciatkowska M, Kim AR, Asara JM, D'Alessandro A, Perrimon N.
Nat Commun
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Nat Commun
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Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration.
Authors: Authors: Madrigal P, Thanki AS, Fexova S, Yu ID, Chatzigeorgiou A, Zucchi I, Marugan Calles JC, Vilmovsky L, Khen A, Zhao L, Erdos K, Kurri SR, Selvakumar S, Kumbham U, Prakash A, Wang S, Green A, Ribas CE, Sweeney B, Alegbe T, Suveges D, Hemrom A, Gomez Gutierrez DE, Insua S, Jeffryes M, Pearce M, Basutkar P, Kaforou M, Cunnington A, Levin M, Kumari S, Ware D, Goutte-Gattat D, Röper K, Brown NH, Hu Y, Perrimon N, Papatheodorou I, Brazma A, Hermjakob H, Harrison M, Ocaña D, Ochoa D, McDonagh EM, Bateman A, Keane T, Vizcaíno JA, Ernst C.
Nucleic Acids Res
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Nucleic Acids Res
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Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila.
Authors: Authors: Lin J, Deng Q, Gao Y, Tan YS, Zhong Z, Tan LKA, Tan BOP, Virshup DM, Bosch JA, Perrimon N, Wang H.
Nat Commun
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Nat Commun
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A Structure-Guided Kinase-Transcription Factor Interactome Atlas Reveals Docking Landscapes of the Kinome.
Authors: Authors: Kim AR, Huang K, Johnson JL, Yaron-Barir TM, Wang K, Cantley LC, Hu Y, Perrimon N.
bioRxiv
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bioRxiv
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Desaturase-dependent secretory functions of hepatocyte-like cells control systemic lipid metabolism during starvation in Drosophila.
Authors: Authors: Li J, Huang K, Dibra I, Liu Y, Perrimon N, Simons M.
Nat Commun
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Nat Commun
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Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila.
Authors: Authors: Han M, Xia B, Kim AR, Filine E, Stoneburner E, Miao T, Liu Y, Zirin J, Perrimon N.
bioRxiv
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bioRxiv
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Hepatic ceramide synthesis links systemic inflammation to organelle dysfunction in cancer.
Authors: Authors: Liu Y, Miao T, Wang A, Dantas E, Kim AR, Zhang Z, Sun X, Binari R, Asara JM, Hu Y, Goncalves MD, Janowitz T, Perrimon N.
bioRxiv
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bioRxiv
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A family of lethal exotoxins defined by cell entry via the Attractin receptor.
Authors: Authors: Viswanatha R, Lee D, Robins WR, Mameli E, Hu Y, Kim AR, Hashmi Y, Nishida H, Prakash G, Butnaru M, Churchman S, Mohr SE, Mekalanos JJ, Perrimon N.
bioRxiv
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bioRxiv
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