Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Renal coenzyme A (CoA) production from VB5 fuels stem cell proliferation and tumor growth.
Authors: Authors: Miao T, Liu Y, Qadiri M, Dasseux A, Asara JM, Hu Y, Sun X, Pliego-Alcántara LDC, Dibble CC, Perrimon N.
Nat Commun
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Nat Commun
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Lipids Regulate Export of Lysosomal Enzymes from the Endoplasmic Reticulum.
DIOPT: the DRSC Integrative Ortholog Prediction Tool, 2026 update.
Authors: Authors: Hu Y, Comjean A, Gao C, Veal A, Yamamoto S, Mohr SE, Perrimon N.
bioRxiv
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bioRxiv
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Phage display-mediated immuno-PCR to detect low-abundance secreted proteins in Drosophila.
Authors: Authors: Han M, Xia B, Kim AR, Filine E, Stoneburner E, Miao T, Liu Y, Zirin J, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Tumor-induced orexigenic imbalance lowers protein appetite and drives early organ wasting symptoms.
Authors: Authors: Petsakou A, Filine E, Li M, Chen Y, Zheng A, Perrimon N.
Nat Commun
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Nat Commun
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Cholinergic signaling modulates intestinal pathophysiology in a Drosophila model of cystic fibrosis.
Authors: Authors: Lane EA, Petsakou A, Liu Y, Chen W, Qadiri M, Hu Y, Perrimon N.
PLoS Genet
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PLoS Genet
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Metabolic command centers in Drosophila: how the fat body and oenocytes orchestrate immunity, reproduction, and aging.
The Drosophila proventriculus lacks stem cells but compensates for age-related cell loss via endoreplication-mediated cell growth.
Authors: Authors: Ewen-Campen B, Chen W, Tattikota SG, Liu Y, Hu Y, Perrimon N.
Nat Commun
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Nat Commun
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Modeling tissue-specific Drosophila metabolism identifies high sugar diet-induced metabolic dysregulation in muscle at reaction and pathway levels.
Authors: Authors: Moon SJ, Hu Y, Dzieciatkowska M, Kim AR, Asara JM, D'Alessandro A, Perrimon N.
Nat Commun
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Nat Commun
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Expression Atlas in 2026: enabling FAIR and open expression data through community collaboration and integration.
Authors: Authors: Madrigal P, Thanki AS, Fexova S, Yu ID, Chatzigeorgiou A, Zucchi I, Marugan Calles JC, Vilmovsky L, Khen A, Zhao L, Erdos K, Kurri SR, Selvakumar S, Kumbham U, Prakash A, Wang S, Green A, Ribas CE, Sweeney B, Alegbe T, Suveges D, Hemrom A, Gomez Gutierrez DE, Insua S, Jeffryes M, Pearce M, Basutkar P, Kaforou M, Cunnington A, Levin M, Kumari S, Ware D, Goutte-Gattat D, Röper K, Brown NH, Hu Y, Perrimon N, Papatheodorou I, Brazma A, Hermjakob H, Harrison M, Ocaña D, Ochoa D, McDonagh EM, Bateman A, Keane T, Vizcaíno JA, Ernst C.
Nucleic Acids Res
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Nucleic Acids Res
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