
Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Krüppel homolog 1 represses insect ecdysone biosynthesis by directly inhibiting the transcription of steroidogenic enzymes.
Authors: Authors: Zhang T, Song W, Li Z, Qian W, Wei L, Yang Y, Wang W, Zhou X, Meng M, Peng J, Xia Q, Perrimon N, Cheng D.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Xio is a component of the Drosophila sex determination pathway and RNA N6-methyladenosine methyltransferase complex.
Authors: Authors: Guo J, Tang HW, Li J, Perrimon N, Yan D.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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A gene-specific T2A-GAL4 library for Drosophila.
Authors: Authors: Lee PT, Zirin J, Kanca O, Lin WW, Schulze KL, Li-Kroeger D, Tao R, Devereaux C, Hu Y, Chung V, Fang Y, He Y, Pan H, Ge M, Zuo Z, Housden BE, Mohr SE, Yamamoto S, Levis RW, Spradling AC, Perrimon N, Bellen HJ.
Elife
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Elife
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Mechanical regulation of stem-cell differentiation by the stretch-activated Piezo channel.
Zinc Detoxification: A Functional Genomics and Transcriptomics Analysis in Drosophila melanogaster Cultured Cells.
Authors: Authors: Mohr SE, Rudd K, Hu Y, Song WR, Gilly Q, Buckner M, Housden BE, Kelley C, Zirin J, Tao R, Amador G, Sierzputowska K, Comjean A, Perrimon N.
G3 (Bethesda)
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G3 (Bethesda)
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Molecular Interaction Search Tool (MIST): an integrated resource for mining gene and protein interaction data.
Authors: Authors: Hu Y, Vinayagam A, Nand A, Comjean A, Chung V, Hao T, Mohr SE, Perrimon N.
Nucleic Acids Res
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Nucleic Acids Res
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Improved detection of synthetic lethal interactions in Drosophila cells using variable dose analysis (VDA).
Authors: Authors: Housden BE, Li Z, Kelley C, Wang Y, Hu Y, Valvezan AJ, Manning BD, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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mTORC1 Couples Nucleotide Synthesis to Nucleotide Demand Resulting in a Targetable Metabolic Vulnerability.
Authors: Authors: Valvezan AJ, Turner M, Belaid A, Lam HC, Miller SK, McNamara MC, Baglini C, Housden BE, Perrimon N, Kwiatkowski DJ, Asara JM, Henske EP, Manning BD.
Cancer Cell
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Cancer Cell
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A Mechanism Coupling Systemic Energy Sensing to Adipokine Secretion.
Authors: Authors: Rajan A, Housden BE, Wirtz-Peitz F, Holderbaum L, Perrimon N.
Dev Cell
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Dev Cell
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Accessing the Phenotype Gap: Enabling Systematic Investigation of Paralog Functional Complexity with CRISPR.