Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
SALS, a WH2-domain-containing protein, promotes sarcomeric actin filament elongation from pointed ends during Drosophila muscle growth.
Functional screening identifies miR-315 as a potent activator of Wingless signaling.
Authors: Authors: Silver SJ, Hagen JW, Okamura K, Perrimon N, Lai EC.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Drosophila and the genetics of the internal milieu.
Intelligent Interfaces for Mining Large-Scale RNAi-HCS Image Databases.
Authors: Authors: Lin C, Mak W, Hong P, Sepp K, Perrimon N.
Proc IEEE Int Symp Bioinformatics Bioeng
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Proc IEEE Int Symp Bioinformatics Bioeng
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Quantitative morphological signatures define local signaling networks regulating cell morphology.
A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression.
Authors: Authors: Lu J, Ruhf ML, Perrimon N, Leder P.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Do-it-yourself RNAi made easy?
Genetic screening for signal transduction in the era of network biology.
Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens.
Authors: Authors: Perrimon N, Friedman A, Mathey-Prevot B, Eggert US.
Drug Discov Today
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Drug Discov Today
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Matter arising: off-targets and genome-scale RNAi screens in Drosophila.