Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan.
Heparan sulfate proteoglycans are essential for FGF receptor signaling during Drosophila embryonic development.
Authors: Authors: Lin X, Buff EM, Perrimon N, Michelson AM.
Development
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Development
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Pattern formation and developmental mechanisms unresolved issues of pattern formation
The latest in signal transduction, 1999. Specificity in Signal Transduction, Keystone, Colorado, USA, 9-14 April 1999.
Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.
I-SceI endonuclease, a new tool for studying DNA double-strand break repair mechanisms in Drosophila.
Polarity determination in the Drosophila eye: a novel role for unpaired and JAK/STAT signaling.
Negative feedback mechanisms and their roles during pattern formation.
The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis.
Authors: Authors: Ghiglione C, Carraway KL, Amundadottir LT, Boswell RE, Perrimon N, Duffy JB.
Cell
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Cell
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Synergistic activities of multiple phosphotyrosine residues mediate full signaling from the Drosophila Torso receptor tyrosine kinase.
Authors: Authors: Gayko U, Cleghon V, Copeland T, Morrison DK, Perrimon N.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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