Norbert Perrimon, Ph.D.
James Stillman Professor of Developmental Biology, Harvard Medical School
Investigator, Howard Hughes Medical Institute
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes.
Approaches to identify genes involved in Drosophila embryonic CNS development.
Authors: Authors: Noll E, Perkins LA, Mahowald AP, Perrimon N.
J Neurobiol
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J Neurobiol
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Developmental and molecular characterization of mutations in the Drosophila-raf serine/threonine protein kinase.
Authors: Authors: Melnick MB, Perkins LA, Lee M, Ambrosio L, Perrimon N.
Development
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Development
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Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila.
Authors: Authors: Lu X, Chou TB, Williams NG, Roberts T, Perrimon N.
Genes Dev
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Genes Dev
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The torso pathway in Drosophila: a model system to study receptor tyrosine kinase signal transduction.
Cell patterning in the Drosophila segment: engrailed and wingless antigen distributions in segment polarity mutant embryos.
Authors: Authors: van den Heuvel M, Klingensmith J, Perrimon N, Nusse R.
Dev Suppl
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Dev Suppl
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wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate.
The Drosophila spitz gene encodes a putative EGF-like growth factor involved in dorsal-ventral axis formation and neurogenesis.
Authors: Authors: Rutledge BJ, Zhang K, Bier E, Jan YN, Perrimon N.
Genes Dev
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Genes Dev
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corkscrew encodes a putative protein tyrosine phosphatase that functions to transduce the terminal signal from the receptor tyrosine kinase torso.
orthodenticle activity is required for the development of medial structures in the larval and adult epidermis of Drosophila.