Olivier Pourquie headshot

Olivier Pourquie, Ph.D.

Professor of Genetics, Harvard Medical School
Frank Burr Mallory Professor of Pathology, Brigham and Women's Hospital
617-755-4724
Pourquie Lab Website

Olivier Pourquie is Professor in the Department of Genetics at Harvard Medical School and Professor of Pathology at the Brigham and Women’s Hospital. He was the director of the Institute for Genetics and Molecular and Cellular Biology (IGBMC) in France and before that a Howard Hughes Medical Institute Investigator at the Stowers Institute for Medical Research in Kansas City. He graduated as an engineer in France and trained with Nicole Le Douarin. He is the Editor in Chief of the journal Development. He was the Editor in Chief of the journal Development from 2009-2018.

Dr. Pourquie authored more than 100 peer-reviewed publications. He is an elected member of the European Molecular Biology Organization and of the Academia Europea. His work on the segmentation clock that controls the periodicity of vertebrae was recognized as one of the milestones in developmental biology of the 20th century by Nature Magazine. In 2020, he was elected as President of the Society for Developmental Biology, and as a member of the National Academy of Sciences.

Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors.
Authors: Authors: Atsuta Y, Lee C, Rodrigues AR, Colle C, Tomizawa RR, Lujan EG, Tschopp P, Galan L, Zhu M, Gorham JM, Vannier JP, Seidman CE, Seidman JG, Ros MA, Pourquié O, Tabin CJ.
Dev Cell
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The Clockwork Embryo: Mechanisms Regulating Developmental Rate.
Authors: Authors: Diaz-Cuadros M, Pourquié O.
Annu Rev Genet
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Reconstructing human brown fat developmental trajectory in vitro.
Authors: Authors: Rao J, Djeffal Y, Chal J, Marchianò F, Wang CH, Al Tanoury Z, Gapon S, Mayeuf-Louchart A, Glass I, Sefton EM, Habermann B, Kardon G, Watt FM, Tseng YH, Pourquié O.
Dev Cell
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Author Correction: Metabolic regulation of species-specific developmental rates.
Authors: Authors: Diaz-Cuadros M, Miettinen TP, Skinner OS, Sheedy D, Díaz-García CM, Gapon S, Hubaud A, Yellen G, Manalis SR, Oldham WM, Pourquié O.
Nature
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Reconstruction and deconstruction of human somitogenesis in vitro.
Authors: Authors: Miao Y, Djeffal Y, De Simone A, Zhu K, Lee JG, Lu Z, Silberfeld A, Rao J, Tarazona OA, Mongera A, Rigoni P, Diaz-Cuadros M, Song LMS, Di Talia S, Pourquié O.
Nature
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Metabolic regulation of species-specific developmental rates.
Authors: Authors: Diaz-Cuadros M, Miettinen TP, Skinner OS, Sheedy D, Díaz-García CM, Gapon S, Hubaud A, Yellen G, Manalis SR, Oldham WM, Pourquié O.
Nature
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A brief history of the segmentation clock.
Authors: Authors: Pourquié O.
Dev Biol
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Generation of LUMCi041-A-2: Equipping a PAX3 reporter iPSC line with doxycycline inducible H2B-mTurquoise2 for live cell imaging.
Authors: Authors: Arendzen CH, Chaudhari U, Cramer SJ, Freund CMAH, Mummery CL, Ranga A, Pourquie O, Mikkers HMM.
Stem Cell Res
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Human muscle production in vitro from pluripotent stem cells: Basic and clinical applications.
Authors: Authors: Yan L, Rodríguez-delaRosa A, Pourquié O.
Semin Cell Dev Biol
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Prednisolone rescues Duchenne muscular dystrophy phenotypes in human pluripotent stem cell-derived skeletal muscle in vitro.
Authors: Authors: Al Tanoury Z, Zimmerman JF, Rao J, Sieiro D, McNamara HM, Cherrier T, Rodríguez-delaRosa A, Hick-Colin A, Bousson F, Fugier-Schmucker C, Marchiano F, Habermann B, Chal J, Nesmith AP, Gapon S, Wagner E, Gupta VA, Bassel-Duby R, Olson EN, Cohen AE, Parker KK, Pourquié O.
Proc Natl Acad Sci U S A
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