Cyclin A2 maintains colon homeostasis and is a prognostic factor in colorectal cancer.
Authors: Authors: Guo Y, Gabola M, Lattanzio R, Paul C, Pinet V, Tang R, Turali H, Bremond J, Longobardi C, Maurizy C, Da Costa Q, Finetti P, Boissière-Michot F, Rivière B, Lemmers C, Garnier S, Bertucci F, Zlobec I, Chebli K, Tazi J, Azar R, Blanchard JM, Sicinski P, Mamessier E, Lemmers B, Hahne M.
J Clin Invest
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J Clin Invest
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Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics.
Authors: Authors: Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE.
J Am Heart Assoc
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J Am Heart Assoc
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A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1.
Authors: Authors: Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D.
Nat Commun
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Nat Commun
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A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2.
Authors: Authors: Zhou J, Tien AC, Alberta JA, Ficarro SB, Griveau A, Sun Y, Deshpande JS, Card JD, Morgan-Smith M, Michowski W, Hashizume R, James CD, Ligon KL, Snider WD, Sicinski P, Marto JA, Rowitch DH, Stiles CD.
Cell Rep
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Cell Rep
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Mammalian E-type cyclins control chromosome pairing, telomere stability and CDK2 localization in male meiosis.
Authors: Authors: Martinerie L, Manterola M, Chung SS, Panigrahi SK, Weisbach M, Vasileva A, Geng Y, Sicinski P, Wolgemuth DJ.
PLoS Genet
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PLoS Genet
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Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.
Authors: Authors: Cole AM, Myant K, Reed KR, Ridgway RA, Athineos D, Van den Brink GR, Muncan V, Clevers H, Clarke AR, Sicinski P, Sansom OJ.
Cancer Res
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Cancer Res
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Roles of cyclins A and E in induction of centrosome amplification in p53-compromised cells.
Authors: Authors: Hanashiro K, Kanai M, Geng Y, Sicinski P, Fukasawa K.
Oncogene
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Oncogene
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Peroxisome proliferator-activated receptor-delta induces cell proliferation by a cyclin E1-dependent mechanism and is up-regulated in thyroid tumors.
Authors: Authors: Zeng L, Geng Y, Tretiakova M, Yu X, Sicinski P, Kroll TG.
Cancer Res
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Cancer Res
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Duality of p27Kip1 function in tumorigenesis.
Cyclins and cdks in development and cancer: a perspective.