Stephen Elledge headshot
Stephen J. Elledge, Ph.D
Gregor Mendel Professor of Genetics and of Medicine
Integrated loss- and gain-of-function screens define a core network governing human embryonic stem cell behavior.
Authors: Authors: Naxerova K, Di Stefano B, Makofske JL, Watson EV, de Kort MA, Martin TD, Dezfulian M, Ricken D, Wooten EC, Kuroda MI, Hochedlinger K, Elledge SJ.
Genes Dev
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Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids.
Authors: Authors: Meng Q, Xie S, Gray GK, Dezfulian MH, Li W, Huang L, Akshinthala D, Ferrer E, Conahan C, Perea Del Pino S, Grossman J, Elledge SJ, Hidalgo M, Muthuswamy SK.
J Immunother Cancer
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High-resolution epitope mapping by AllerScan reveals relationships between IgE and IgG repertoires during peanut oral immunotherapy.
Authors: Authors: Chen G, Shrock EL, Li MZ, Spergel JM, Nadeau KC, Pongracic JA, Umetsu DT, Rachid R, MacGinnitie AJ, Phipatanakul W, Schneider L, Oettgen HC, Elledge SJ.
Cell Rep Med
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The Protexin complex counters resection on stalled forks to promote homologous recombination and crosslink repair.
Authors: Authors: Adeyemi RO, Willis NA, Elia AEH, Clairmont C, Li S, Wu X, D'Andrea AD, Scully R, Elledge SJ.
Mol Cell
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The adaptive immune system is a major driver of selection for tumor suppressor gene inactivation.
Authors: Authors: Martin TD, Patel RS, Cook DR, Choi MY, Patil A, Liang AC, Li MZ, Haigis KM, Elledge SJ.
Science
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CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays.
Authors: Authors: Barber KW, Shrock E, Elledge SJ.
Mol Cell
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Coordinate regulation of the senescent state by selective autophagy.
Authors: Authors: Lee Y, Kim J, Kim MS, Kwon Y, Shin S, Yi H, Kim H, Chang MJ, Chang CB, Kang SB, Kim VN, Kim JH, Kim JS, Elledge SJ, Kang C.
Dev Cell
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ORF10-Cullin-2-ZYG11B complex is not required for SARS-CoV-2 infection.
Authors: Authors: Mena EL, Donahue CJ, Vaites LP, Li J, Rona G, O'Leary C, Lignitto L, Miwatani-Minter B, Paulo JA, Dhabaria A, Ueberheide B, Gygi SP, Pagano M, Harper JW, Davey RA, Elledge SJ.
Proc Natl Acad Sci U S A
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Antibody responses to endemic coronaviruses modulate COVID-19 convalescent plasma functionality.
Authors: Authors: Morgenlander WR, Henson SN, Monaco DR, Chen A, Littlefield K, Bloch EM, Fujimura E, Ruczinski I, Crowley AR, Natarajan H, Butler SE, Weiner JA, Li MZ, Bonny TS, Benner SE, Balagopal A, Sullivan D, Shoham S, Quinn TC, Eshleman SH, Casadevall A, Redd AD, Laeyendecker O, Ackerman ME, Pekosz A, Elledge SJ, Robinson M, Tobian AA, Larman HB.
J Clin Invest
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Systematic characterization of mutations altering protein degradation in human cancers.
Authors: Authors: Tokheim C, Wang X, Timms RT, Zhang B, Mena EL, Wang B, Chen C, Ge J, Chu J, Zhang W, Elledge SJ, Brown M, Liu XS.
Mol Cell
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