Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits.
Authors:
Nat Biotechnol
View full abstract on Pubmed
Proteasomal control of anti-CRISPRs for the regulation of CRISPR/Cas9 activity using Cas9-ACROBAT.
Authors: Authors: Martin TD, Watson EV, Choi MY, Nabet B, Gray NS, Xu Q, Elledge SJ.
bioRxiv
View full abstract on Pubmed
Mechanism of ?-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase.
Authors: Authors: Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C.
Nat Commun
View full abstract on Pubmed
Serologic Response to the Epstein-Barr Virus Peptidome and the Risk for Multiple Sclerosis.
Authors: Authors: Cortese M, Leng Y, Bjornevik K, Mitchell M, Healy BC, Mina MJ, Mancuso JD, Niebuhr DW, Munger KL, Elledge SJ, Ascherio A.
JAMA Neurol
View full abstract on Pubmed
Chromosome evolution screens recapitulate tissue-specific tumor aneuploidy patterns.
Authors: Authors: Watson EV, Lee JJ, Gulhan DC, Melloni GEM, Venev SV, Magesh RY, Frederick A, Chiba K, Wooten EC, Naxerova K, Dekker J, Park PJ, Elledge SJ.
Nat Genet
View full abstract on Pubmed
Efficient encoding of large antigenic spaces by epitope prioritization with Dolphyn.
Authors: Authors: Liebhoff AM, Venkataraman T, Morgenlander WR, Na M, Kula T, Waugh K, Morrison C, Rewers M, Longman R, Round J, Elledge S, Ruczinski I, Langmead B, Larman HB.
Nat Commun
View full abstract on Pubmed
Author Correction: Defining E3 ligase-substrate relationships through multiplex CRISPR screening.
Authors: Authors: Timms RT, Mena EL, Leng Y, Li MZ, Tchasovnikarova IA, Koren I, Elledge SJ.
Nat Cell Biol
View full abstract on Pubmed
Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping.
Authors: Authors: Zhang Z, Sie B, Chang A, Leng Y, Nardone C, Timms RT, Elledge SJ.
Mol Cell
View full abstract on Pubmed
TScan-II: A genome-scale platform for the de novo identification of CD4+ T cell epitopes.
Authors: Authors: Dezfulian MH, Kula T, Pranzatelli T, Kamitaki N, Meng Q, Khatri B, Perez P, Xu Q, Chang A, Kohlgruber AC, Leng Y, Jupudi AA, Joachims ML, Chiorini JA, Lessard CJ, Darise Farris A, Muthuswamy SK, Warner BM, Elledge SJ.
Cell
View full abstract on Pubmed
Elucidation of E3 ubiquitin ligase specificity through proteome-wide internal degron mapping.
Authors: Authors: Zhang Z, Sie B, Chang A, Leng Y, Nardone C, Timms RT, Elledge SJ.
Mol Cell
View full abstract on Pubmed