Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.

Authors: Authors: Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K.
Stem Cell Reports 2016-05-10
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How autophagy both activates and inhibits cellular senescence.

Authors: Authors: Kang C, Elledge SJ.
Autophagy 2016-05-03
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A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling.

Authors: Authors: Wang Y, Xu Q, Sack L, Kang C, Elledge SJ.
Genes Dev 2016-02-01
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Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.

Authors: Authors: Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK.
Cell Host Microbe 2015-12-09
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FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency.

Authors: Authors: Huang H, Santoso N, Power D, Simpson S, Dieringer M, Miao H, Gurova K, Giam CZ, Elledge SJ, Zhu J.
J Biol Chem 2015-11-06
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RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.

Authors: Authors: Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ.
Mol Cell 2015-10-15
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The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.

Authors: Authors: Kang C, Xu Q, Martin TD, Li MZ, Demaria M, Aron L, Lu T, Yankner BA, Campisi J, Elledge SJ.
Science 2015-09-25
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The DNA Damage Response--Self-awareness for DNA: The 2015 Albert Lasker Basic Medical Research Award.

Authors: Authors: Elledge SJ.
JAMA 2015-09-15
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Accidents and Damage Control.

Authors: Authors: Elledge SJ.
Cell 2015-09-10
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Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.

Authors: Authors: Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.
Mol Cell 2015-09-03
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