Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.
Authors: Authors: Kang C, Xu Q, Martin TD, Li MZ, Demaria M, Aron L, Lu T, Yankner BA, Campisi J, Elledge SJ.
Science
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The DNA Damage Response--Self-awareness for DNA: The 2015 Albert Lasker Basic Medical Research Award.
Authors: Authors: Elledge SJ.
JAMA
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Accidents and Damage Control.
Authors: Authors: Elledge SJ.
Cell
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Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.
Authors: Authors: Elia AE, Boardman AP, Wang DC, Huttlin EL, Everley RA, Dephoure N, Zhou C, Koren I, Gygi SP, Elledge SJ.
Mol Cell
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Taking the brakes off telomerase.
Authors: Authors: Naxerova K, Elledge SJ.
Elife
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A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors.
Authors: Authors: Izhar L, Adamson B, Ciccia A, Lewis J, Pontano-Vaites L, Leng Y, Liang AC, Westbrook TF, Harper JW, Elledge SJ.
Cell Rep
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Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome.
Authors: Authors: Xu GJ, Kula T, Xu Q, Li MZ, Vernon SD, Ndung'u T, Ruxrungtham K, Sanchez J, Brander C, Chung RT, O'Connor KC, Walker B, Larman HB, Elledge SJ.
Science
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NatB domain-containing CRA-1 antagonizes hydrolase ACER-1 linking acetyl-CoA metabolism to the initiation of recombination during C. elegans meiosis.
Authors: Authors: Gao J, Kim HM, Elia AE, Elledge SJ, Colaiácovo MP.
PLoS Genet
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Homologous-recombination-deficient tumours are dependent on Pol?-mediated repair.
Authors: Authors: Ceccaldi R, Liu JC, Amunugama R, Hajdu I, Primack B, Petalcorin MI, O'Connor KW, Konstantinopoulos PA, Elledge SJ, Boulton SJ, Yusufzai T, D'Andrea AD.
Nature
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Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.
Authors: Authors: Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ.
Proc Natl Acad Sci U S A
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