Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

The CD225 domain of IFITM3 is required for both IFITM protein association and inhibition of influenza A virus and dengue virus replication.

Authors: Authors: John SP, Chin CR, Perreira JM, Feeley EM, Aker AM, Savidis G, Smith SE, Elia AE, Everitt AR, Vora M, Pertel T, Elledge SJ, Kellam P, Brass AL.
J Virol 2013-07-01
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PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis.

Authors: Authors: Larman HB, Laserson U, Querol L, Verhaeghen K, Solimini NL, Xu GJ, Klarenbeek PL, Church GM, Hafler DA, Plenge RM, Nigrovic PA, De Jager PL, Weets I, Martens GA, O'Connor KC, Elledge SJ.
J Autoimmun 2013-06-01
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A role for PVRL4-driven cell-cell interactions in tumorigenesis.

Authors: Authors: Pavlova NN, Pallasch C, Elia AE, Braun CJ, Westbrook TF, Hemann M, Elledge SJ.
Elife 2013-04-30
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Characterization of Torin2, an ATP-competitive inhibitor of mTOR, ATM, and ATR.

Authors: Authors: Liu Q, Xu C, Kirubakaran S, Zhang X, Hur W, Liu Y, Kwiatkowski NP, Wang J, Westover KD, Gao P, Ercan D, Niepel M, Thoreen CC, Kang SA, Patricelli MP, Wang Y, Tupper T, Altabef A, Kawamura H, Held KD, Chou DM, Elledge SJ, Janne PA, Wong KK, Sabatini DM, Gray NS.
Cancer Res 2013-04-15
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Protein interaction discovery using parallel analysis of translated ORFs (PLATO).

Authors: Authors: Zhu J, Larman HB, Gao G, Somwar R, Zhang Z, Laserson U, Ciccia A, Pavlova N, Church G, Zhang W, Kesari S, Elledge SJ.
Nat Biotechnol 2013-04-01
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Cytosolic 5'-nucleotidase 1A autoimmunity in sporadic inclusion body myositis.

Authors: Authors: Larman HB, Salajegheh M, Nazareno R, Lam T, Sauld J, Steen H, Kong SW, Pinkus JL, Amato AA, Elledge SJ, Greenberg SA.
Ann Neurol 2013-03-01
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Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila.

Authors: Authors: Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI.
Nat Struct Mol Biol 2013-02-01
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STOP gene Phactr4 is a tumor suppressor.

Authors: Authors: Solimini NL, Liang AC, Xu C, Pavlova NN, Xu Q, Davoli T, Li MZ, Wong KK, Elledge SJ.
Proc Natl Acad Sci U S A 2013-01-29
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Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10.

Authors: Authors: Finton KA, Larimore K, Larman HB, Friend D, Correnti C, Rupert PB, Elledge SJ, Greenberg PD, Strong RK.
PLoS Pathog 2013-01-01
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Construction of a rationally designed antibody platform for sequencing-assisted selection.

Authors: Authors: Larman HB, Xu GJ, Pavlova NN, Elledge SJ.
Proc Natl Acad Sci U S A 2012-11-06
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