Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Elledge Lab Website

Additional Websites
Publications

HHMI Investigator

Cytosolic 5'-nucleotidase 1A autoimmunity in sporadic inclusion body myositis.

Authors: Authors: Larman HB, Salajegheh M, Nazareno R, Lam T, Sauld J, Steen H, Kong SW, Pinkus JL, Amato AA, Elledge SJ, Greenberg SA.
Ann Neurol 2013-03-01
View full abstract on Pubmed

Chromatin proteins captured by ChIP-mass spectrometry are linked to dosage compensation in Drosophila.

Authors: Authors: Wang CI, Alekseyenko AA, LeRoy G, Elia AE, Gorchakov AA, Britton LM, Elledge SJ, Kharchenko PV, Garcia BA, Kuroda MI.
Nat Struct Mol Biol 2013-02-01
View full abstract on Pubmed

STOP gene Phactr4 is a tumor suppressor.

Authors: Authors: Solimini NL, Liang AC, Xu C, Pavlova NN, Xu Q, Davoli T, Li MZ, Wong KK, Elledge SJ.
Proc Natl Acad Sci U S A 2013-01-29
View full abstract on Pubmed

Autoreactivity and exceptional CDR plasticity (but not unusual polyspecificity) hinder elicitation of the anti-HIV antibody 4E10.

Authors: Authors: Finton KA, Larimore K, Larman HB, Friend D, Correnti C, Rupert PB, Elledge SJ, Greenberg PD, Strong RK.
PLoS Pathog 2013-01-01
View full abstract on Pubmed

Construction of a rationally designed antibody platform for sequencing-assisted selection.

Authors: Authors: Larman HB, Xu GJ, Pavlova NN, Elledge SJ.
Proc Natl Acad Sci U S A 2012-11-06
View full abstract on Pubmed

Systematic identification of synergistic drug pairs targeting HIV.

Authors: Authors: Tan X, Hu L, Luquette LJ, Gao G, Liu Y, Qu H, Xi R, Lu ZJ, Park PJ, Elledge SJ.
Nat Biotechnol 2012-11-01
View full abstract on Pubmed

Reactivation of latent HIV-1 by inhibition of BRD4.

Authors: Authors: Zhu J, Gaiha GD, John SP, Pertel T, Chin CR, Gao G, Qu H, Walker BD, Elledge SJ, Brass AL.
Cell Rep 2012-10-25
View full abstract on Pubmed

Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress.

Authors: Authors: Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ.
Mol Cell 2012-08-10
View full abstract on Pubmed

Recurrent hemizygous deletions in cancers may optimize proliferative potential.

Authors: Authors: Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ.
Science 2012-07-06
View full abstract on Pubmed

BRCA1 as tumor suppressor: lord without its RING?

Authors: Authors: Elia AE, Elledge SJ.
Breast Cancer Res 2012-04-10
View full abstract on Pubmed