Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

Authors: Authors: Luo J, Emanuele MJ, Li D, Creighton CJ, Schlabach MR, Westbrook TF, Wong KK, Elledge SJ.
Cell 2009-05-29
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A genome-wide RNAi screen identifies a new transcriptional module required for self-renewal.

Authors: Authors: Hu G, Kim J, Xu Q, Leng Y, Orkin SH, Elledge SJ.
Genes Dev 2009-04-01
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NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.

Authors: Authors: Wang B, Hurov K, Hofmann K, Elledge SJ.
Genes Dev 2009-03-15
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Principles of cancer therapy: oncogene and non-oncogene addiction.

Authors: Authors: Luo J, Solimini NL, Elledge SJ.
Cell 2009-03-06
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Design of 240,000 orthogonal 25mer DNA barcode probes.

Authors: Authors: Xu Q, Schlabach MR, Hannon GJ, Elledge SJ.
Proc Natl Acad Sci U S A 2009-02-17
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A role for the host coatomer and KDEL receptor in early vaccinia biogenesis.

Authors: Authors: Zhang L, Lee SY, Beznoussenko GV, Peters PJ, Yang JS, Gilbert HY, Brass AL, Elledge SJ, Isaacs SN, Moss B, Mironov A, Hsu VW.
Proc Natl Acad Sci U S A 2009-01-06
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WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity.

Authors: Authors: Xiao A, Li H, Shechter D, Ahn SH, Fabrizio LA, Erdjument-Bromage H, Ishibe-Murakami S, Wang B, Tempst P, Hofmann K, Patel DJ, Elledge SJ, Allis CD.
Nature 2009-01-01
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CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.

Authors: Authors: Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y.
Mol Cell 2008-12-05
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FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.

Authors: Authors: Collis SJ, Ciccia A, Deans AJ, Horejsí Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ, West SC, Boulton SJ.
Mol Cell 2008-11-07
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Identification of SCF ubiquitin ligase substrates by global protein stability profiling.

Authors: Authors: Yen HC, Elledge SJ.
Science 2008-11-07
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