Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
Global protein stability profiling in mammalian cells.
Identification of MSA1, a cell cycle-regulated, dosage suppressor of drc1/sld2 and dpb11 mutants.
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.
Authors: Authors: Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M.
Nat Struct Mol Biol
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Nat Struct Mol Biol
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Dif1 is a DNA-damage-regulated facilitator of nuclear import for ribonucleotide reductase.
RNA interference screen for human genes associated with West Nile virus infection.
Authors: Authors: Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, Sultana H, Brass AL, Adametz R, Tsui M, Qian F, Montgomery RR, Lev S, Mason PW, Koski RA, Elledge SJ, Xavier RJ, Agaisse H, Fikrig E.
Nature
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Nature
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A quantitative atlas of mitotic phosphorylation.
Authors: Authors: Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Cancer: Deconstructing oncogenesis.
How ATR turns on: TopBP1 goes on ATRIP with ATR.
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.
Authors: Authors: Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A, Leng Y, Maehr R, Shi Y, Harper JW, Elledge SJ.
Nature
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Nature
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Identification of host proteins required for HIV infection through a functional genomic screen.
Authors: Authors: Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science
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Science
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