Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
A quantitative atlas of mitotic phosphorylation.
Authors: Authors: Dephoure N, Zhou C, Villén J, Beausoleil SA, Bakalarski CE, Elledge SJ, Gygi SP.
Proc Natl Acad Sci U S A
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Cancer: Deconstructing oncogenesis.
Authors: Authors: Luo J, Elledge SJ.
Nature
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How ATR turns on: TopBP1 goes on ATRIP with ATR.
Authors: Authors: Burrows AE, Elledge SJ.
Genes Dev
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SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.
Authors: Authors: Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A, Leng Y, Maehr R, Shi Y, Harper JW, Elledge SJ.
Nature
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Identification of host proteins required for HIV infection through a functional genomic screen.
Authors: Authors: Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science
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Profiling essential genes in human mammary cells by multiplex RNAi screening.
Authors: Authors: Silva JM, Marran K, Parker JS, Silva J, Golding M, Schlabach MR, Elledge SJ, Hannon GJ, Chang K.
Science
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Cancer proliferation gene discovery through functional genomics.
Authors: Authors: Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ.
Science
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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
Authors: Authors: Wang B, Elledge SJ.
Proc Natl Acad Sci U S A
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The DNA damage response: ten years after.
Authors: Authors: Harper JW, Elledge SJ.
Mol Cell
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RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling.
Authors: Authors: Stewart GS, Stankovic T, Byrd PJ, Wechsler T, Miller ES, Huissoon A, Drayson MT, West SC, Elledge SJ, Taylor AM.
Proc Natl Acad Sci U S A
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