Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

Cancer proliferation gene discovery through functional genomics.

Authors: Authors: Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ.
Science 2008-02-01
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Profiling essential genes in human mammary cells by multiplex RNAi screening.

Authors: Authors: Silva JM, Marran K, Parker JS, Silva J, Golding M, Schlabach MR, Elledge SJ, Hannon GJ, Chang K.
Science 2008-02-01
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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.

Authors: Authors: Wang B, Elledge SJ.
Proc Natl Acad Sci U S A 2007-12-26
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The DNA damage response: ten years after.

Authors: Authors: Harper JW, Elledge SJ.
Mol Cell 2007-12-14
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RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling.

Authors: Authors: Stewart GS, Stankovic T, Byrd PJ, Wechsler T, Miller ES, Huissoon A, Drayson MT, West SC, Elledge SJ, Taylor AM.
Proc Natl Acad Sci U S A 2007-10-23
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Non-oncogene addiction and the stress phenotype of cancer cells.

Authors: Authors: Solimini NL, Luo J, Elledge SJ.
Cell 2007-09-21
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The ubiquitin-specific protease USP28 is required for MYC stability.

Authors: Authors: Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, Moll R, Elledge SJ, Eilers M.
Nat Cell Biol 2007-07-01
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Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.

Authors: Authors: Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ.
Science 2007-05-25
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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Authors: Authors: Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.
Science 2007-05-25
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The tumor suppressor CYLD regulates entry into mitosis.

Authors: Authors: Stegmeier F, Sowa ME, Nalepa G, Gygi SP, Harper JW, Elledge SJ.
Proc Natl Acad Sci U S A 2007-05-22
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