Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Elledge Lab Website

Additional Websites
Publications

HHMI Investigator

How ATR turns on: TopBP1 goes on ATRIP with ATR.

Authors: Authors: Burrows AE, Elledge SJ.
Genes Dev 2008-06-01
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SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation.

Authors: Authors: Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A, Leng Y, Maehr R, Shi Y, Harper JW, Elledge SJ.
Nature 2008-03-20
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Identification of host proteins required for HIV infection through a functional genomic screen.

Authors: Authors: Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science 2008-02-15
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Profiling essential genes in human mammary cells by multiplex RNAi screening.

Authors: Authors: Silva JM, Marran K, Parker JS, Silva J, Golding M, Schlabach MR, Elledge SJ, Hannon GJ, Chang K.
Science 2008-02-01
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Cancer proliferation gene discovery through functional genomics.

Authors: Authors: Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ.
Science 2008-02-01
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Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.

Authors: Authors: Wang B, Elledge SJ.
Proc Natl Acad Sci U S A 2007-12-26
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The DNA damage response: ten years after.

Authors: Authors: Harper JW, Elledge SJ.
Mol Cell 2007-12-14
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RIDDLE immunodeficiency syndrome is linked to defects in 53BP1-mediated DNA damage signaling.

Authors: Authors: Stewart GS, Stankovic T, Byrd PJ, Wechsler T, Miller ES, Huissoon A, Drayson MT, West SC, Elledge SJ, Taylor AM.
Proc Natl Acad Sci U S A 2007-10-23
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Non-oncogene addiction and the stress phenotype of cancer cells.

Authors: Authors: Solimini NL, Luo J, Elledge SJ.
Cell 2007-09-21
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The ubiquitin-specific protease USP28 is required for MYC stability.

Authors: Authors: Popov N, Wanzel M, Madiredjo M, Zhang D, Beijersbergen R, Bernards R, Moll R, Elledge SJ, Eilers M.
Nat Cell Biol 2007-07-01
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