Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Elledge Lab Website

Additional Websites
Publications

HHMI Investigator

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function.

Authors: Authors: Chou DM, Elledge SJ.
Proc Natl Acad Sci U S A 2006-11-28
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Lessons from Nature: microRNA-based shRNA libraries.

Authors: Authors: Chang K, Elledge SJ, Hannon GJ.
Nat Methods 2006-09-01
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A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response.

Authors: Authors: Zhang D, Zaugg K, Mak TW, Elledge SJ.
Cell 2006-08-11
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Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress.

Authors: Authors: Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L.
Mol Cell 2006-08-04
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ATM-Chk2-p53 activation prevents tumorigenesis at an expense of organ homeostasis upon Brca1 deficiency.

Authors: Authors: Cao L, Kim S, Xiao C, Wang RH, Coumoul X, Wang X, Li WM, Xu XL, De Soto JA, Takai H, Mai S, Elledge SJ, Motoyama N, Deng CX.
EMBO J 2006-05-17
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Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.

Authors: Authors: Lee YD, Elledge SJ.
Genes Dev 2006-02-01
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The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.

Authors: Authors: Turnell AS, Stewart GS, Grand RJ, Rookes SM, Martin A, Yamano H, Elledge SJ, Gallimore PH.
Nature 2005-12-01
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53BP1 oligomerization is independent of its methylation by PRMT1.

Authors: Authors: Adams MM, Wang B, Xia Z, Morales JC, Lu X, Donehower LA, Bochar DA, Elledge SJ, Carpenter PB.
Cell Cycle 2005-12-01
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Second-generation shRNA libraries covering the mouse and human genomes.

Authors: Authors: Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ.
Nat Genet 2005-11-01
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An open letter to cancer researchers.

Authors: Authors: Elledge SJ, Hannon GJ.
Science 2005-10-21
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