Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.
Authors: Authors: Lee YD, Elledge SJ.
Genes Dev
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53BP1 oligomerization is independent of its methylation by PRMT1.
Authors: Authors: Adams MM, Wang B, Xia Z, Morales JC, Lu X, Donehower LA, Bochar DA, Elledge SJ, Carpenter PB.
Cell Cycle
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The APC/C and CBP/p300 cooperate to regulate transcription and cell-cycle progression.
Authors: Authors: Turnell AS, Stewart GS, Grand RJ, Rookes SM, Martin A, Yamano H, Elledge SJ, Gallimore PH.
Nature
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Second-generation shRNA libraries covering the mouse and human genomes.
Authors: Authors: Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ.
Nat Genet
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An open letter to cancer researchers.
Authors: Authors: Elledge SJ, Hannon GJ.
Science
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BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1-Chk1 pathway, implicating checkpoint dysfunction in microcephaly.
Authors: Authors: Lin SY, Rai R, Li K, Xu ZX, Elledge SJ.
Proc Natl Acad Sci U S A
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A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells.
Authors: Authors: Stegmeier F, Hu G, Rickles RJ, Hannon GJ, Elledge SJ.
Proc Natl Acad Sci U S A
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umuDC and mucAB operons whose products are required for UV light- and chemical-induced mutagenesis: UmuD, MucA, and LexA proteins share homology. 1985.
Authors: Authors: Perry KL, Elledge SJ, Mitchell BB, Marsh L, Walker GC.
DNA Repair (Amst)
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A genetic screen for candidate tumor suppressors identifies REST.
Authors: Authors: Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ.
Cell
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An open letter to Elias Zerhouni.
Authors: Authors: Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N.
Science
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