Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
The two faces of BRCA2, a FANCtastic discovery.
The SUMO-1 isopeptidase Smt4 is linked to centromeric cohesion through SUMO-1 modification of DNA topoisomerase II.
Authors: Authors: Bachant J, Alcasabas A, Blat Y, Kleckner N, Elledge SJ.
Mol Cell
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Mol Cell
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Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex.
Authors: Authors: Zheng N, Schulman BA, Song L, Miller JJ, Jeffrey PD, Wang P, Chu C, Koepp DM, Elledge SJ, Pagano M, Conaway RC, Conaway JW, Harper JW, Pavletich NP.
Nature
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Nature
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Genetic and physical interactions between DPB11 and DDC1 in the yeast DNA damage response pathway.
The BRCA1 suppressor hypothesis: an explanation for the tissue-specific tumor development in BRCA1 patients.
The mitotic spindle is required for loading of the DASH complex onto the kinetochore.
Authors: Authors: Li Y, Bachant J, Alcasabas AA, Wang Y, Qin J, Elledge SJ.
Genes Dev
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Genes Dev
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Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin.
Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway.
Towards genetic genome projects: genomic library screening and gene-targeting vector construction in a single step.
Bub2 is a cell cycle regulated phospho-protein controlled by multiple checkpoints.