Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Asf1 links Rad53 to control of chromatin assembly.
Authors: Authors: Hu F, Alcasabas AA, Elledge SJ.
Genes Dev
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Transcriptional regulation and function during the human cell cycle.
Authors: Authors: Cho RJ, Huang M, Campbell MJ, Dong H, Steinmetz L, Sapinoso L, Hampton G, Elledge SJ, Davis RW, Lockhart DJ.
Nat Genet
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The cellular chamber of doom.
Authors: Authors: Goldberg AL, Elledge SJ, Harper JW.
Sci Am
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Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
Authors: Authors: Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT.
Genes Dev
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The DNA damage response: putting checkpoints in perspective.
Authors: Authors: Zhou BB, Elledge SJ.
Nature
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Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.
Authors: Authors: Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ER, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP.
Nature
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The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit.
Authors: Authors: Wang Y, Hu F, Elledge SJ.
Curr Biol
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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.
Authors: Authors: Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ.
Proc Natl Acad Sci U S A
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Conducting the mitotic symphony.
Authors: Authors: Cortez D, Elledge SJ.
Nature
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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
Authors: Authors: Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, Luo G, Carattini-Rivera S, DeMayo F, Bradley A, Donehower LA, Elledge SJ.
Genes Dev
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