Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex.

Authors: Authors: Schulman BA, Carrano AC, Jeffrey PD, Bowen Z, Kinnucan ER, Finnin MS, Elledge SJ, Harper JW, Pagano M, Pavletich NP.
Nature 2000-11-16
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The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit.

Authors: Authors: Wang Y, Hu F, Elledge SJ.
Curr Biol 2000-11-02
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Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro.

Authors: Authors: Matsuoka S, Rotman G, Ogawa A, Shiloh Y, Tamai K, Elledge SJ.
Proc Natl Acad Sci U S A 2000-09-12
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Conducting the mitotic symphony.

Authors: Authors: Cortez D, Elledge SJ.
Nature 2000-07-27
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Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.

Authors: Authors: Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, Luo G, Carattini-Rivera S, DeMayo F, Bradley A, Donehower LA, Elledge SJ.
Genes Dev 2000-06-15
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Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination.

Authors: Authors: Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinecke P, Richieri-Costa A, Zackai EH, Massagué J, Muenke M, Elledge SJ.
Nat Genet 2000-06-01
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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.

Authors: Authors: Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J.
Genes Dev 2000-04-15
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DNA damage-induced activation of p53 by the checkpoint kinase Chk2.

Authors: Authors: Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW.
Science 2000-03-10
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The multifunctional character of a geminivirus replication protein is reflected by its complex oligomerization properties.

Authors: Authors: Orozco BM, Kong LJ, Batts LA, Elledge S, Hanley-Bowdoin L.
J Biol Chem 2000-03-03
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p53 sends nucleotides to repair DNA.

Authors: Authors: Lozano G, Elledge SJ.
Nature 2000-03-02
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