
Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
Conducting the mitotic symphony.
Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint.
Authors: Authors: Liu Q, Guntuku S, Cui XS, Matsuoka S, Cortez D, Tamai K, Luo G, Carattini-Rivera S, DeMayo F, Bradley A, Donehower LA, Elledge SJ.
Genes Dev
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Genes Dev
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Mutations in TGIF cause holoprosencephaly and link NODAL signalling to human neural axis determination.
Authors: Authors: Gripp KW, Wotton D, Edwards MC, Roessler E, Ades L, Meinecke P, Richieri-Costa A, Zackai EH, Massagué J, Muenke M, Elledge SJ.
Nat Genet
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Nat Genet
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BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
Authors: Authors: Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J.
Genes Dev
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Genes Dev
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DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Authors: Authors: Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW.
Science
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Science
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The multifunctional character of a geminivirus replication protein is reflected by its complex oligomerization properties.
Authors: Authors: Orozco BM, Kong LJ, Batts LA, Elledge S, Hanley-Bowdoin L.
J Biol Chem
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J Biol Chem
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p53 sends nucleotides to repair DNA.
The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway.
Authors: Authors: Huang M, Elledge SJ.
Cold Spring Harb Symp Quant Biol
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Cold Spring Harb Symp Quant Biol
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Rapid construction of recombinant DNA by the univector plasmid-fusion system.
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.
Authors: Authors: Caspary T, Cleary MA, Perlman EJ, Zhang P, Elledge SJ, Tilghman SM.
Genes Dev
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Genes Dev
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