Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
Rapid construction of recombinant DNA by the univector plasmid-fusion system.
The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway.
Authors: Authors: Huang M, Elledge SJ.
Cold Spring Harb Symp Quant Biol
View full abstract on Pubmed
Cold Spring Harb Symp Quant Biol
View full abstract on Pubmed
Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.
Authors: Authors: Caspary T, Cleary MA, Perlman EJ, Zhang P, Elledge SJ, Tilghman SM.
Genes Dev
View full abstract on Pubmed
Genes Dev
View full abstract on Pubmed
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.
Authors: Authors: Sanchez Y, Bachant J, Wang H, Hu F, Liu D, Tetzlaff M, Elledge SJ.
Science
View full abstract on Pubmed
Science
View full abstract on Pubmed
A family of mammalian F-box proteins.
Authors: Authors: Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
Curr Biol
View full abstract on Pubmed
Curr Biol
View full abstract on Pubmed
New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.
Authors: Authors: Ouspenski II, Elledge SJ, Brinkley BR.
Nucleic Acids Res
View full abstract on Pubmed
Nucleic Acids Res
View full abstract on Pubmed
SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.
Authors: Authors: Kitagawa K, Skowyra D, Elledge SJ, Harper JW, Hieter P.
Mol Cell
View full abstract on Pubmed
Mol Cell
View full abstract on Pubmed
How the cyclin became a cyclin: regulated proteolysis in the cell cycle.
Skipping into the E2F1-destruction pathway.