Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.
Authors: Authors: Sanchez Y, Bachant J, Wang H, Hu F, Liu D, Tetzlaff M, Elledge SJ.
Science
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Science
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A family of mammalian F-box proteins.
Authors: Authors: Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
Curr Biol
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Curr Biol
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New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.
Authors: Authors: Ouspenski II, Elledge SJ, Brinkley BR.
Nucleic Acids Res
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Nucleic Acids Res
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SGT1 encodes an essential component of the yeast kinetochore assembly pathway and a novel subunit of the SCF ubiquitin ligase complex.
Authors: Authors: Kitagawa K, Skowyra D, Elledge SJ, Harper JW, Hieter P.
Mol Cell
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Mol Cell
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How the cyclin became a cyclin: regulated proteolysis in the cell cycle.
Skipping into the E2F1-destruction pathway.
Mitotic treasures in the nucleolus.
Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Authors: Authors: Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW.
Science
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Science
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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Authors: Authors: Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW.
Science
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Science
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