Stephen J. Elledge

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital

Professor of Medicine, Brigham and Women's Hospital

617-525-4510

Additional Websites
Publications

DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.

Authors: Authors: Wang H, Elledge SJ.
Proc Natl Acad Sci U S A 1999-03-30
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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.

Authors: Authors: Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW.
Genes Dev 1999-02-01
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p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step.

Authors: Authors: Zhang P, Wong C, Liu D, Finegold M, Harper JW, Elledge SJ.
Genes Dev 1999-01-15
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Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo.

Authors: Authors: Gómez Lahoz E, Liegeois NJ, Zhang P, Engelman JA, Horner J, Silverman A, Burde R, Roussel MF, Sherr CJ, Elledge SJ, DePinho RA.
Mol Cell Biol 1999-01-01
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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.

Authors: Authors: Matsuoka S, Huang M, Elledge SJ.
Science 1998-12-04
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The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes.

Authors: Authors: Liu Q, Li MZ, Leibham D, Cortez D, Elledge SJ.
Curr Biol 1998-12-03
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Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development.

Authors: Authors: Zhang P, Wong C, DePinho RA, Harper JW, Elledge SJ.
Genes Dev 1998-10-15
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Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway.

Authors: Authors: Desany BA, Alcasabas AA, Bachant JB, Elledge SJ.
Genes Dev 1998-09-15
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The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor.

Authors: Authors: Huang M, Zhou Z, Elledge SJ.
Cell 1998-09-04
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Human cyclin K, a novel RNA polymerase II-associated cyclin possessing both carboxy-terminal domain kinase and Cdk-activating kinase activity.

Authors: Authors: Edwards MC, Wong C, Elledge SJ.
Mol Cell Biol 1998-07-01
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