Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
Mitotic treasures in the nucleolus.
Authors: Authors: Bachant JB, Elledge SJ.
Nature
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Rbx1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase.
Authors: Authors: Kamura T, Koepp DM, Conrad MN, Skowyra D, Moreland RJ, Iliopoulos O, Lane WS, Kaelin WG, Elledge SJ, Conaway RC, Harper JW, Conaway JW.
Science
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Reconstitution of G1 cyclin ubiquitination with complexes containing SCFGrr1 and Rbx1.
Authors: Authors: Skowyra D, Koepp DM, Kamura T, Conrad MN, Conaway RC, Conaway JW, Elledge SJ, Harper JW.
Science
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DRC1, DNA replication and checkpoint protein 1, functions with DPB11 to control DNA replication and the S-phase checkpoint in Saccharomyces cerevisiae.
Authors: Authors: Wang H, Elledge SJ.
Proc Natl Acad Sci U S A
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The SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitro.
Authors: Authors: Winston JT, Strack P, Beer-Romero P, Chu CY, Elledge SJ, Harper JW.
Genes Dev
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p21(CIP1) and p57(KIP2) control muscle differentiation at the myogenin step.
Authors: Authors: Zhang P, Wong C, Liu D, Finegold M, Harper JW, Elledge SJ.
Genes Dev
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Cyclin D- and E-dependent kinases and the p57(KIP2) inhibitor: cooperative interactions in vivo.
Authors: Authors: Gómez Lahoz E, Liegeois NJ, Zhang P, Engelman JA, Horner J, Silverman A, Burde R, Roussel MF, Sherr CJ, Elledge SJ, DePinho RA.
Mol Cell Biol
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Linkage of ATM to cell cycle regulation by the Chk2 protein kinase.
Authors: Authors: Matsuoka S, Huang M, Elledge SJ.
Science
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The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes.
Authors: Authors: Liu Q, Li MZ, Leibham D, Cortez D, Elledge SJ.
Curr Biol
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Cooperation between the Cdk inhibitors p27(KIP1) and p57(KIP2) in the control of tissue growth and development.
Authors: Authors: Zhang P, Wong C, DePinho RA, Harper JW, Elledge SJ.
Genes Dev
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