Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Authors: Authors: Hirao A, Kong YY, Matsuoka S, Wakeham A, Ruland J, Yoshida H, Liu D, Elledge SJ, Mak TW.
Science
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The multifunctional character of a geminivirus replication protein is reflected by its complex oligomerization properties.
Authors: Authors: Orozco BM, Kong LJ, Batts LA, Elledge S, Hanley-Bowdoin L.
J Biol Chem
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p53 sends nucleotides to repair DNA.
Authors: Authors: Lozano G, Elledge SJ.
Nature
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Rapid construction of recombinant DNA by the univector plasmid-fusion system.
Authors: Authors: Liu Q, Li MZ, Liu D, Elledge SJ.
Methods Enzymol
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The FHA domain, a phosphoamino acid binding domain involved in the DNA damage response pathway.
Authors: Authors: Huang M, Elledge SJ.
Cold Spring Harb Symp Quant Biol
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Oppositely imprinted genes p57(Kip2) and igf2 interact in a mouse model for Beckwith-Wiedemann syndrome.
Authors: Authors: Caspary T, Cleary MA, Perlman EJ, Zhang P, Elledge SJ, Tilghman SM.
Genes Dev
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Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
Authors: Authors: Cortez D, Wang Y, Qin J, Elledge SJ.
Science
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Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms.
Authors: Authors: Sanchez Y, Bachant J, Wang H, Hu F, Liu D, Tetzlaff M, Elledge SJ.
Science
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A family of mammalian F-box proteins.
Authors: Authors: Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
Curr Biol
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New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.
Authors: Authors: Ouspenski II, Elledge SJ, Brinkley BR.
Nucleic Acids Res
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