Stephen J. Elledge, Ph.D.
Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
The role of protein stability in the cell cycle and cancer.
Mitotic arrest: Mad2 prevents sleepy from waking up the APC.
The role of Cdk7 in CAK function, a retro-retrospective.
G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts.
Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
Authors: Authors: Edwards MC, Liegeois N, Horecka J, DePinho RA, Sprague GF, Tyers M, Elledge SJ.
Genetics
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Genetics
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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.
Authors: Authors: Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW.
Cell
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Cell
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Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae.
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Authors: Authors: Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ.
Science
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Science
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Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.
Authors: Authors: Lee MP, DeBaun M, Randhawa G, Reichard BA, Elledge SJ, Feinberg AP.
Am J Hum Genet
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Am J Hum Genet
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Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.
Authors: Authors: Aronheim A, Zandi E, Hennemann H, Elledge SJ, Karin M.
Mol Cell Biol
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Mol Cell Biol
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