Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Authors: Authors: Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ.
Science
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Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.
Authors: Authors: Lee MP, DeBaun M, Randhawa G, Reichard BA, Elledge SJ, Feinberg AP.
Am J Hum Genet
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Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.
Authors: Authors: Aronheim A, Zandi E, Hennemann H, Elledge SJ, Karin M.
Mol Cell Biol
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Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome.
Authors: Authors: Zhang P, Liégeois NJ, Wong C, Finegold M, Hou H, Thompson JC, Silverman A, Harper JW, DePinho RA, Elledge SJ.
Nature
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Analysis of budding yeast kinases controlled by DNA damage.
Authors: Authors: Sanchez Y, Zhou Z, Huang M, Kemp BE, Elledge SJ.
Methods Enzymol
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Gene identification using the yeast two-hybrid system.
Authors: Authors: Bai C, Elledge SJ.
Methods Enzymol
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Purification and analysis of CIP/KIP proteins.
Authors: Authors: Dynlacht BD, Ngwu C, Winston J, Swindell EC, Elledge SJ, Harlow E, Harper JW.
Methods Enzymol
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Cell cycle checkpoints: preventing an identity crisis.
Authors: Authors: Elledge SJ.
Science
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Cyclin D2 is an FSH-responsive gene involved in gonadal cell proliferation and oncogenesis.
Authors: Authors: Sicinski P, Donaher JL, Geng Y, Parker SB, Gardner H, Park MY, Robker RL, Richards JS, McGinnis LK, Biggers JD, Eppig JJ, Bronson RT, Elledge SJ, Weinberg RA.
Nature
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RAD9 and DNA polymerase epsilon form parallel sensory branches for transducing the DNA damage checkpoint signal in Saccharomyces cerevisiae.
Authors: Authors: Navas TA, Sanchez Y, Elledge SJ.
Genes Dev
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