Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
The role of Cdk7 in CAK function, a retro-retrospective.
Authors: Authors: Harper JW, Elledge SJ.
Genes Dev
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G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts.
Authors: Authors: Connell-Crowley L, Elledge SJ, Harper JW.
Curr Biol
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Human CPR (cell cycle progression restoration) genes impart a Far- phenotype on yeast cells.
Authors: Authors: Edwards MC, Liegeois N, Horecka J, DePinho RA, Sprague GF, Tyers M, Elledge SJ.
Genetics
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F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex.
Authors: Authors: Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW.
Cell
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Identification of RNR4, encoding a second essential small subunit of ribonucleotide reductase in Saccharomyces cerevisiae.
Authors: Authors: Huang M, Elledge SJ.
Mol Cell Biol
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Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25.
Authors: Authors: Sanchez Y, Wong C, Thoma RS, Richman R, Wu Z, Piwnica-Worms H, Elledge SJ.
Science
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Low frequency of p57KIP2 mutation in Beckwith-Wiedemann syndrome.
Authors: Authors: Lee MP, DeBaun M, Randhawa G, Reichard BA, Elledge SJ, Feinberg AP.
Am J Hum Genet
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Isolation of an AP-1 repressor by a novel method for detecting protein-protein interactions.
Authors: Authors: Aronheim A, Zandi E, Hennemann H, Elledge SJ, Karin M.
Mol Cell Biol
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Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith-Wiedemann syndrome.
Authors: Authors: Zhang P, Liégeois NJ, Wong C, Finegold M, Hou H, Thompson JC, Silverman A, Harper JW, DePinho RA, Elledge SJ.
Nature
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Purification and analysis of CIP/KIP proteins.
Authors: Authors: Dynlacht BD, Ngwu C, Winston J, Swindell EC, Elledge SJ, Harlow E, Harper JW.
Methods Enzymol
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