Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
Authors: Authors: Flores-Rozas H, Kelman Z, Dean FB, Pan ZQ, Harper JW, Elledge SJ, O'Donnell M, Hurwitz J.
Proc Natl Acad Sci U S A
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Isolation of a cDNA encoding a metal response element binding protein using a novel expression cloning procedure: the one hybrid system.
Authors: Authors: Inouye C, Remondelli P, Karin M, Elledge S.
DNA Cell Biol
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Specific association between the human DNA repair proteins XPA and ERCC1.
Authors: Authors: Li L, Elledge SJ, Peterson CA, Bales ES, Legerski RJ.
Proc Natl Acad Sci U S A
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p53-dependent inhibition of cyclin-dependent kinase activities in human fibroblasts during radiation-induced G1 arrest.
Authors: Authors: Dulic V, Kaufmann WK, Wilson SJ, Tlsty TD, Lees E, Harper JW, Elledge SJ, Reed SI.
Cell
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Cloning of the complete coding region for human protein phosphatase inhibitor 2 using the two hybrid system and expression of inhibitor 2 in E. coli.
Authors: Authors: Helps NR, Street AJ, Elledge SJ, Cohen PT.
FEBS Lett
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DUN1 encodes a protein kinase that controls the DNA damage response in yeast.
Authors: Authors: Zhou Z, Elledge SJ.
Cell
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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases.
Authors: Authors: Harper JW, Adami GR, Wei N, Keyomarsi K, Elledge SJ.
Cell
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Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1.
Authors: Authors: Zhang XF, Settleman J, Kyriakis JM, Takeuchi-Suzuki E, Elledge SJ, Marshall MS, Bruder JT, Rapp UR, Avruch J.
Nature
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Amplification of cyclin genes in colorectal carcinomas.
Authors: Authors: Leach FS, Elledge SJ, Sherr CJ, Willson JK, Markowitz S, Kinzler KW, Vogelstein B.
Cancer Res
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DNA damage and cell cycle regulation of ribonucleotide reductase.
Authors: Authors: Elledge SJ, Zhou Z, Allen JB, Navas TA.
Bioessays
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