Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Diversified Application of Barcoded PLATO (PLATO-BC) Platform for Identification of Protein Interactions.
Authors: Authors: Kong W, Hayashi T, Fiches G, Xu Q, Li MZ, Que J, Liu S, Zhang W, Qi J, Santoso N, Elledge SJ, Zhu J.
Genomics Proteomics Bioinformatics
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Temporal virus serological profiling of kidney graft recipients using VirScan.
Authors: Authors: Isnard P, Kula T, Avettand Fenoel V, Anglicheau D, Terzi F, Legendre C, Elledge SJ, Canaud G.
Proc Natl Acad Sci U S A
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Comprehensive Profiling of HIV Antibody Evolution.
Authors: Authors: Eshleman SH, Laeyendecker O, Kammers K, Chen A, Sivay MV, Kottapalli S, Sie BM, Yuan T, Monaco DR, Mohan D, Wansley D, Kula T, Morrison C, Elledge SJ, Brookmeyer R, Ruczinski I, Larman HB.
Cell Rep
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MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.
Authors: Authors: Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K.
Cancer Discov
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Tissue-specificity in cancer: The rule, not the exception.
Authors: Authors: Haigis KM, Cichowski K, Elledge SJ.
Science
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Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets.
Authors: Authors: Mengwasser KE, Adeyemi RO, Leng Y, Choi MY, Clairmont C, D'Andrea AD, Elledge SJ.
Mol Cell
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Sequencer Hacking Unlocks Quantitative Protein Studies.
Authors: Authors: Barber KW, Elledge SJ.
Mol Cell
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A Druggable Genome Screen Identifies Modifiers of a-Synuclein Levels via a Tiered Cross-Species Validation Approach.
Authors: Authors: Rousseaux MWC, Vázquez-Vélez GE, Al-Ramahi I, Jeong HH, Bajic A, Revelli JP, Ye H, Phan ET, Deger JM, Perez AM, Kim JY, Lavery LA, Xu Q, Li MZ, Kang H, Kim JJ, Shulman JM, Westbrook TF, Elledge SJ, Liu Z, Botas J, Zoghbi HY.
J Neurosci
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Life-threatening influenza pneumonitis in a child with inherited IRF9 deficiency.
Authors: Authors: Hernandez N, Melki I, Jing H, Habib T, Huang SSY, Danielson J, Kula T, Drutman S, Belkaya S, Rattina V, Lorenzo-Diaz L, Boulai A, Rose Y, Kitabayashi N, Rodero MP, Dumaine C, Blanche S, Lebras MN, Leung MC, Mathew LS, Boisson B, Zhang SY, Boisson-Dupuis S, Giliani S, Chaussabel D, Notarangelo LD, Elledge SJ, Ciancanelli MJ, Abel L, Zhang Q, Marr N, Crow YJ, Su HC, Casanova JL.
J Exp Med
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Genetic modifiers of the BRD4-NUT dependency of NUT midline carcinoma uncovers a synergism between BETis and CDK4/6is.
Authors: Authors: Liao S, Maertens O, Cichowski K, Elledge SJ.
Genes Dev
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