Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program.
Authors: Authors: Mazzucco AE, Smogorzewska A, Kang C, Luo J, Schlabach MR, Xu Q, Patel R, Elledge SJ.
Genes Dev
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Aneuploidy Police Detect Chromosomal Imbalance Triggering Immune Crackdown!
Authors: Authors: Watson EV, Elledge SJ.
Trends Genet
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Reply.
Authors: Authors: Shah AA, Rosen A, Hummers LK, Wigley FM, Xu G, Elledge SJ, Casciola-Rosen L.
Arthritis Rheumatol
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A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.
Authors: Authors: Martin TD, Cook DR, Choi MY, Li MZ, Haigis KM, Elledge SJ.
Cell Rep
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Origins of lymphatic and distant metastases in human colorectal cancer.
Authors: Authors: Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK.
Science
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Brief Report: Anti-RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma.
Authors: Authors: Shah AA, Xu G, Rosen A, Hummers LK, Wigley FM, Elledge SJ, Casciola-Rosen L.
Arthritis Rheumatol
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Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
Authors: Authors: Davoli T, Uno H, Wooten EC, Elledge SJ.
Science
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A genetic interaction analysis identifies cancer drivers that modify EGFR dependency.
Authors: Authors: Liao S, Davoli T, Leng Y, Li MZ, Xu Q, Elledge SJ.
Genes Dev
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Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
Authors: Authors: Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ.
Genes Dev
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Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer.
Authors: Authors: Xu GJ, Shah AA, Li MZ, Xu Q, Rosen A, Casciola-Rosen L, Elledge SJ.
Proc Natl Acad Sci U S A
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