Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Origins of lymphatic and distant metastases in human colorectal cancer.
Authors: Authors: Naxerova K, Reiter JG, Brachtel E, Lennerz JK, van de Wetering M, Rowan A, Cai T, Clevers H, Swanton C, Nowak MA, Elledge SJ, Jain RK.
Science
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Brief Report: Anti-RNPC-3 Antibodies As a Marker of Cancer-Associated Scleroderma.
Authors: Authors: Shah AA, Xu G, Rosen A, Hummers LK, Wigley FM, Elledge SJ, Casciola-Rosen L.
Arthritis Rheumatol
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Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
Authors: Authors: Davoli T, Uno H, Wooten EC, Elledge SJ.
Science
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A genetic interaction analysis identifies cancer drivers that modify EGFR dependency.
Authors: Authors: Liao S, Davoli T, Leng Y, Li MZ, Xu Q, Elledge SJ.
Genes Dev
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Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover.
Authors: Authors: Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ.
Genes Dev
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Systematic autoantigen analysis identifies a distinct subtype of scleroderma with coincident cancer.
Authors: Authors: Xu GJ, Shah AA, Li MZ, Xu Q, Rosen A, Casciola-Rosen L, Elledge SJ.
Proc Natl Acad Sci U S A
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Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Authors: Authors: Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, Sun D, Elledge SJ, Alessi DR, Kahle KT.
Sci Rep
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Sources of Error in Mammalian Genetic Screens.
Authors: Authors: Sack LM, Davoli T, Xu Q, Li MZ, Elledge SJ.
G3 (Bethesda)
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Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks.
Authors: Authors: Zhou C, Elia AE, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ.
Proc Natl Acad Sci U S A
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Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.
Authors: Authors: Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N.
Proc Natl Acad Sci U S A
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