Stephen Elledge headshot

Stephen J. Elledge, Ph.D.

Gregor Mendel Professor of Genetics and of Medicine, Brigham and Women's Hospital
Professor of Medicine, Brigham and Women's Hospital
617-525-4510
Elledge Lab Website
Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Authors: Authors: Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, Sun D, Elledge SJ, Alessi DR, Kahle KT.
Sci Rep
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Sources of Error in Mammalian Genetic Screens.
Authors: Authors: Sack LM, Davoli T, Xu Q, Li MZ, Elledge SJ.
G3 (Bethesda)
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Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks.
Authors: Authors: Willis NA, Zhou C, Elia AE, Murray JM, Carr AM, Elledge SJ, Rhind N.
Proc Natl Acad Sci U S A
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Profiling DNA damage-induced phosphorylation in budding yeast reveals diverse signaling networks.
Authors: Authors: Zhou C, Elia AE, Naylor ML, Dephoure N, Ballif BA, Goel G, Xu Q, Ng A, Chou DM, Xavier RJ, Gygi SP, Elledge SJ.
Proc Natl Acad Sci U S A
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A Serial shRNA Screen for Roadblocks to Reprogramming Identifies the Protein Modifier SUMO2.
Authors: Authors: Borkent M, Bennett BD, Lackford B, Bar-Nur O, Brumbaugh J, Wang L, Du Y, Fargo DC, Apostolou E, Cheloufi S, Maherali N, Elledge SJ, Hu G, Hochedlinger K.
Stem Cell Reports
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How autophagy both activates and inhibits cellular senescence.
Authors: Authors: Kang C, Elledge SJ.
Autophagy
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A gain-of-function senescence bypass screen identifies the homeobox transcription factor DLX2 as a regulator of ATM-p53 signaling.
Authors: Authors: Wang Y, Xu Q, Sack L, Kang C, Elledge SJ.
Genes Dev
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Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.
Authors: Authors: Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK.
Cell Host Microbe
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FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency.
Authors: Authors: Huang H, Santoso N, Power D, Simpson S, Dieringer M, Miao H, Gurova K, Giam CZ, Elledge SJ, Zhu J.
J Biol Chem
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RFWD3-Dependent Ubiquitination of RPA Regulates Repair at Stalled Replication Forks.
Authors: Authors: Elia AE, Wang DC, Willis NA, Boardman AP, Hajdu I, Adeyemi RO, Lowry E, Gygi SP, Scully R, Elledge SJ.
Mol Cell
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