Steven A. McCarroll

Steven A. McCarroll, Ph.D.

Dorothy and Milton Flier Professor of Biomedical Science and Genetics

617-432-7794

Publications

Single-nucleus sequencing reveals enriched expression of genetic risk factors in extratelencephalic neurons sensitive to degeneration in ALS.

Authors:
Nat Aging 2024-06-21
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Kynurenic acid inflammatory signaling expands in primates and impairs prefrontal cortical cognition.

Authors:
bioRxiv 2024-06-13
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Genetic drivers and cellular selection of female mosaic X chromosome loss.

Authors:
Nature 2024-06-12
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Key Roles of CACNA1C/Cav1.2 and CALB1/Calbindin in Prefrontal Neurons Altered in Cognitive Disorders.

Authors: Authors: Datta D, Yang S, Joyce MKP, Woo E, McCarroll SA, Gonzalez-Burgos G, Perone I, Uchendu S, Ling E, Goldman M, Berretta S, Murray J, Morozov Y, Arellano J, Duque A, Rakic P, O'Dell R, van Dyck CH, Lewis DA, Wang M, Krienen FM, Arnsten AFT.
JAMA Psychiatry 2024-05-22
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Protein-altering variants at copy number-variable regions influence diverse human phenotypes.

Authors: Authors: Hujoel MLA, Handsaker RE, Sherman MA, Kamitaki N, Barton AR, Mukamel RE, Terao C, McCarroll SA, Loh PR.
Nat Genet 2024-03-28
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CSMD1 regulates brain complement activity and circuit development.

Authors: Authors: Baum ML, Wilton DK, Fox RG, Carey A, Hsu YH, Hu R, Jäntti HJ, Fahey JB, Muthukumar AK, Salla N, Crotty W, Scott-Hewitt N, Bien E, Sabatini DA, Lanser TB, Frouin A, Gergits F, Håvik B, Gialeli C, Nacu E, Lage K, Blom AM, Eggan K, McCarroll SA, Johnson MB, Stevens B.
Brain Behav Immun 2024-03-27
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Modeling interpretable correspondence between cell state and perturbation response with CellCap.

Authors: Authors: Xu Y, Fleming S, Tegtmeyer M, McCarroll SA, Babadi M.
bioRxiv 2024-03-16
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A concerted neuron-astrocyte program declines in ageing and schizophrenia.

Authors: Authors: Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker RE, Genovese G, Vogelgsang JS, Gerges S, Kashin S, Ghosh S, Esposito JM, Morris K, Meyer D, Lutservitz A, Mullally CD, Wysoker A, Spina L, Neumann A, Hogan M, Ichihara K, Berretta S, McCarroll SA.
Nature 2024-03-01
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Concerted neuron-astrocyte gene expression declines in aging and schizophrenia.

Authors: Authors: Ling E, Nemesh J, Goldman M, Kamitaki N, Reed N, Handsaker RE, Genovese G, Vogelgsang JS, Gerges S, Kashin S, Ghosh S, Esposito JM, French K, Meyer D, Lutservitz A, Mullally CD, Wysoker A, Spina L, Neumann A, Hogan M, Ichihara K, Berretta S, McCarroll SA.
bioRxiv 2024-01-08
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High-dimensional phenotyping to define the genetic basis of cellular morphology.

Authors: Authors: Tegtmeyer M, Arora J, Asgari S, Cimini BA, Nadig A, Peirent E, Liyanage D, Way GP, Weisbart E, Nathan A, Amariuta T, Eggan K, Haghighi M, McCarroll SA, O'Connor L, Carpenter AE, Singh S, Nehme R, Raychaudhuri S.
Nat Commun 2024-01-06
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