Gary Ruvkun headshot

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School
Department of Molecular Biology, Massachusetts General Hospital
617-726-5959
Ruvkun Lab Website
Control of developmental timing by micrornas and their targets.
Authors: Authors: Pasquinelli AE, Ruvkun G.
Annu Rev Cell Dev Biol
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Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway.
Authors: Authors: Lee RY, Hench J, Ruvkun G.
Curr Biol
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Molecular biology. Glimpses of a tiny RNA world.
Authors: Authors: Ruvkun G.
Science
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Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing.
Authors: Authors: Grishok A, Pasquinelli AE, Conte D, Li N, Parrish S, Ha I, Baillie DL, Fire A, Ruvkun G, Mello CC.
Cell
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Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways.
Authors: Authors: Cahill CM, Tzivion G, Nasrin N, Ogg S, Dore J, Ruvkun G, Alexander-Bridges M.
J Biol Chem
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Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family.
Authors: Authors: Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G.
Genes Dev
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Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.
Authors: Authors: Bürglin TR, Ruvkun G.
Development
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Isoform-specific mutations in the Caenorhabditis elegans heterochronic gene lin-14 affect stage-specific patterning.
Authors: Authors: Reinhart BJ, Ruvkun G.
Genetics
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The genetics of aging.
Authors: Authors: Finch CE, Ruvkun G.
Annu Rev Genomics Hum Genet
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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.
Authors: Authors: Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G.
Nature
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