Gary B. Ruvkun

Gary B. Ruvkun, Ph.D.

Professor of Genetics, Harvard Medical School

Department of Molecular Biology, Massachusetts General Hospital

617-726-5959

Ruvkun Lab Website

Publications

Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family.

Authors: Authors: Pierce SB, Costa M, Wisotzkey R, Devadhar S, Homburger SA, Buchman AR, Ferguson KC, Heller J, Platt DM, Pasquinelli AA, Liu LX, Doberstein SK, Ruvkun G.
Genes Dev 2001-03-15
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Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6.

Authors: Authors: Bürglin TR, Ruvkun G.
Development 2001-03-01
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Isoform-specific mutations in the Caenorhabditis elegans heterochronic gene lin-14 affect stage-specific patterning.

Authors: Authors: Reinhart BJ, Ruvkun G.
Genetics 2001-01-01
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The genetics of aging.

Authors: Authors: Finch CE, Ruvkun G.
Annu Rev Genomics Hum Genet 2001-01-01
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Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA.

Authors: Authors: Pasquinelli AE, Reinhart BJ, Slack F, Martindale MQ, Kuroda MI, Maller B, Hayward DC, Ball EE, Degnan B, Müller P, Spring J, Srinivasan A, Fishman M, Finnerty J, Corbo J, Levine M, Leahy P, Davidson E, Ruvkun G.
Nature 2000-11-02
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Graded expression of ceh-14 reporters in the hypodermis is induced by a gonadal signal.

Authors: Authors: Kagoshima H, Sommer R, Reinhart BJ, Cassata G, Ruvkun G, Bürglin TR.
Dev Genes Evol 2000-11-01
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Regulation of C. elegans life-span by insulinlike signaling in the nervous system.

Authors: Authors: Wolkow CA, Kimura KD, Lee MS, Ruvkun G.
Science 2000-10-06
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DAF-16 recruits the CREB-binding protein coactivator complex to the insulin-like growth factor binding protein 1 promoter in HepG2 cells.

Authors: Authors: Nasrin N, Ogg S, Cahill CM, Biggs W, Nui S, Dore J, Calvo D, Shi Y, Ruvkun G, Alexander-Bridges MC.
Proc Natl Acad Sci U S A 2000-09-12
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The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.

Authors: Authors: Slack FJ, Basson M, Liu Z, Ambros V, Horvitz HR, Ruvkun G.
Mol Cell 2000-04-01
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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans.

Authors: Authors: Reinhart BJ, Slack FJ, Basson M, Pasquinelli AE, Bettinger JC, Rougvie AE, Horvitz HR, Ruvkun G.
Nature 2000-02-24
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